148914-36-7Relevant academic research and scientific papers
Ring Expansion of 1-Indanones to 2-Halo-1-naphthols as an Entry Point to Gilvocarcin Natural Products
Zamarija, Ivica,Marsh, Benjamin J.,Magauer, Thomas
supporting information, p. 9221 - 9226 (2021/11/30)
Herein, we describe a two-step ring expansion of 1-indanones to afford 2-chloro/bromo-1-naphthols (32 examples). The developed method shows broad functional group tolerance, benefits from mild reaction conditions, and enables rapid access to the tetracyclic core of gilvocarcin natural products. The orthogonally functionalized products allow for selective postmodifications as exemplified in the total synthesis of defucogilvocarcin M. For the selective oxidation of the chromene, a mild and regioselective oxidation protocol (DDQ and TBHP) was developed.
High-pressure hetero-diels-alder route to (±)-6,6,6-trifluoro- β-C-naphthyl glycosides
Maingot, Lucie,Leconte, Stephane,Chataigner, Isabelle,Martel, Arnaud,Dujardin, Gilles
supporting information; experimental part, p. 1619 - 1622 (2009/09/06)
The first de novo synthesis of a β-C-naphthyl glycoside displaying a convenient functionality for subsequent transformations into complex C-aryl glycosides is reported. The synthesis of this (±)-β-C-1,5- dibenzyloxynaphthyl 6,6,6-trifluoro-3-amino glycosi
