148946-34-3

Upstream product

• 96517-64-5 ethyl (3-cyano-6-phenyl-4-methylpyridinylthio)acetate 
• 67-63-0 isopropyl alcohol 
• 54364-12-4 4-methyl-6-phenyl-2-thioxo-1,2-dihydro-pyridine-3-carbonitrile 

Relevant academic research and scientific papers

Synthesis of N-(2-carboxy-thieno[2,3-b]pyridine-3-yl)-formamidines and corresponding alkyl esters with antianaphylactic activity

A lot of N-(2-carboxy-thieno[2,3-b]pyridin-3-yl)formamidines especially in form of their amine salts - were synthesized by reaction of 3-amino-thieno[2,3-b]pyridine-2-carboxylic acids with dimethylformamide/phosphoroxide chloride or by reaction of 4-oxo-4 H-pyrido[3',2':4,5]thieno[3,2-d]1,3-oxazines with amines. Carboxylic acid alkylesters of this structure were yielded from 3-amino-thieno[2,3-b]pyridine-2-carbonic acid alkylesters by reaction with dimethylformamide/phosphoroxide chloride or with N-formyl-piperidine or N-formyl-morpholine and phosphoroxide chloride. The compounds showed antianaphylactic activity.