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(R)-(+)-2-METHYL-1-PHENYL-1-PROPANOL, also known as α-methylbenzyl alcohol, is a chiral alcohol compound with the chemical formula C10H14O. It is a clear, colorless liquid characterized by a floral, slightly sweet odor and is soluble in organic solvents. (R)-(+)-2-METHYL-1-PHENYL-1-PROPANOL is distinguished by its asymmetrical carbon center, making it a significant intermediate in organic synthesis and a chiral building block in the synthesis of pharmaceuticals and agrochemicals.

14898-86-3

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14898-86-3 Usage

Uses

Used in the Food and Cosmetic Industries:
(R)-(+)-2-METHYL-1-PHENYL-1-PROPANOL is used as a fragrance and flavoring agent for its pleasant scent and taste, enhancing the sensory experience of various products.
Used in Pharmaceutical and Agrochemical Synthesis:
(R)-(+)-2-METHYL-1-PHENYL-1-PROPANOL is used as a chiral building block for its asymmetrical carbon center, playing a crucial role in the development of new pharmaceuticals and agrochemicals.
Used in Organic Synthesis:
(R)-(+)-2-METHYL-1-PHENYL-1-PROPANOL is used as an important intermediate in organic synthesis, facilitating the creation of complex organic compounds.
Used in Neuroprotective Research:
(R)-(+)-2-METHYL-1-PHENYL-1-PROPANOL is studied as a potential neuroprotective agent for its potential use in the treatment of central nervous system disorders, showing promise in certain preclinical studies.

Check Digit Verification of cas no

The CAS Registry Mumber 14898-86-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,8,9 and 8 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 14898-86:
(7*1)+(6*4)+(5*8)+(4*9)+(3*8)+(2*8)+(1*6)=153
153 % 10 = 3
So 14898-86-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H14O/c1-8(2)10(11)9-6-4-3-5-7-9/h3-8,10-11H,1-2H3/t10-/m1/s1

14898-86-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (R)-(+)-2-METHYL-1-PHENYL-1-PROPANOL

1.2 Other means of identification

Product number -
Other names (+)-(R)-2-imethyl-1-phenylpropan-1-ol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:14898-86-3 SDS

14898-86-3Relevant academic research and scientific papers

Ruthenium(II)-catalyzed asymmetric transfer hydrogenation of ketones using chiral oxazolinylferrocenylphosphines and one of their Ru(II) complex

Arikawa, Yasuyoshi,Ueoka, Masanao,Matoba, Kazutaka,Nishibayashi, Yoshiaki,Hidai, Masanobu,Uemura, Sakae

, p. 163 - 168 (1999)

Chiral oxazolinylferrocenylphosphines act as efficient ligands for Ru(II)-catalyzed asymmetric transfer hydrogenation of a variety of alkyl aryl ketones and alkyl methyl ketones to give the corresponding alcohols in moderate yield with moderate-to-good en

Newly designed catalysts for the enantioselective borohydride reduction: Prediction from the theoretical analysis

Ikeno, Taketo,Iwakura, Izumi,Shibahara, Atsushi,Hatanaka, Miho,Kokura, Ai,Tanaka, Saiko,Nagata, Takushi,Yamada, Tohru

, p. 738 - 739 (2007)

For the catalytic enantioselective borohydride reduction, the theoretical simulation of various axial groups in Co complex catalysts predicted that the Co-carbene complexes could be employed as efficient catalysts. The newly designed complexes generated f

Highly efficient chiral PNNP ligand for asymmetric transfer hydrogenation of aromatic ketones in water

Xing, Yan,Chen, Jian-Shan,Dong, Zhen-Rong,Li, Yan-Yun,Gao, Jing-Xing

, p. 4501 - 4503 (2006)

Chiral PNNP ligand II and [IrHCl2(COD)]2 were applied for the first time in the asymmetric transfer hydrogenation of aromatic ketones with HCOONa in water, giving the corresponding optical alcohols in high yield and excellent enantio

Iridium complexes of chiral diamines containing carbon and nitrogen stereocentres: Synthesis, structure and evaluation as transfer hydrogenation catalysts

Fuentes, Jose A.,France, Marcia B.,Slawin, Alexandra M. Z.,Clarke, Matthew L.

, p. 466 - 470 (2009)

Novel Rh(iii) and Ir(iii) complexes of a chiral diamine ligand have been synthesised and structurally characterised. Both complexes were formed as a single diastereomeric species with a single configuration at nitrogen. Ir complexes of the chiral diamine

Chiral Discrimination towards Racemic Alcohols through Host/Guest Clathrate Inclusion with Axially Chiral 1,1'-Binaphthyl-2,2'-dicarboxylic Acid

Kanoh, Shigeyoshi,Hongoh, Yukihiko,Katoh, Shingo,Motoi, Masatoshi,Suda, Hiroshi

, p. 405 - 406 (1988)

Axially chiral 1,1'-binaphthyl-2,2'-dicarboxylic acid (1) was successfully utilised as a new type of chiral host molecule soluble in aqueous alkaline solution; 1-phenylalkan-1-ols were optically resolved by means of chiral host/guest chlatrate inclusion giving optical purities ranging from 18 to 90percent enantiomeric excess (e.e.) depending on the alkyl group.

Alkylmetal Asymmetric Reduction. 13. A Sterically Crowded Chiral Organoaluminum Compound as a Reducing Agent of Ketones

Giacomelli, Giampaolo,Lardicci, Luciano,Palla, Fabio

, p. 310 - 313 (1984)

Optically active carbinols were obtained by reducing the corresponding ketones with heptan-2-yl>methyl>aluminum dichloride.The reactions, which have been carried out at room temperature, are fast and afforded the carbinols in good chemical and optical yields.The extent of the enantioselectivity, along with the stereochemistry of the process, was found to depend on the structure of the ketone employed.The overall results indicated that the present reducing method may be a convenient route to obtain secondary alcohols of high enantiomeric purity under mild conditions.

First green synthesis of (R)-2-methyl-1-phenylpropan-1-ol using whole-cell Lactobacillus paracasei BD101 biotransformation

?ahin, Engin

, p. 138 - 143 (2020)

Green chemistry includes a novel process in the production of drugs precursors and biological active molecules using biocatalysts, so reducing the threats for human sanitary and ecological pollutions. Asymmetric bioreduction of prochiral ketones by biocat

Enantioselective enzymatic reductions of sterically bulky aryl alkyl ketones catalyzed by a NADPH-dependent carbonyl reductase

Zhu, Dunming,Hua, Ling

, p. 9484 - 9486 (2006)

(Chemical Equation Presented) The enantioselective reductions of aryl alkyl ketones, ArC-(O)R, with a diverse number of alkyl groups have been achieved with an isolated carbonyl reductase from Sporobolomyces salmonicolor. Of special interest is the observ

Chiral thiourea as ligand for the asymmetric reduction of prochiral ketones

Touchard, Francois,Gamez, Patrick,Fache, Fabienne,Lemaire, Marc

, p. 2275 - 2278 (1997)

The catalytic enantioselective reduction of prochiral ketones using a chiral thiourea as ligand is reported. Several metallic precursors were tested. e.e.'s up to 94% are obtained with a ruthenium complex.

Highly efficient chiral metal cluster systems derived from Ru3(CO)12 and chiral diiminodiphosphines for the asymmetric transfer hydrogenation of ketones

Zhang, Hui,Yang, Chuan-Bo,Li, Yan-Yun,Donga, Zhen-Rong,Gao, Jing-Xing,Nakamura, Hideaki,Murata, Kunihiko,Ikariya, Takao

, p. 142 - 143 (2003)

The chiral Ru cluster-based catalyst systems generated in situ from Ru3(CO)12 and chiral diiminodiphosphine tetradentate ligands effected asymmetric transfer hydrogenation of propiophenone in 2-propanol, leading to 1-phenyl-1-propano

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