149019-85-2Relevant academic research and scientific papers
Facile synthesis of substituted arylthioureas in the presence of sodium hydride
Cao, Qiang,Liu, Fang,Wang, Min,Xu, Wan,Zeng, Meng-Tian,Liu, Min,Li, Yue-Sheng,Dong, Zhi-Bing
, p. 301 - 303 (2017)
A series of 11 1,1-dimethyl-3-aryl-thioureas were synthesised in good yields (70-92%) by reacting arylamines with S-aryl-N,Ndimethylthiocarbamate in DMSO in the presence of NaH at 90 °C. It is noteworthy that this method can also be used for arylamines containing a halogen atom at the ortho position.
Insertion of arynes into thioureas: A new amidine synthesis
Biswas, Kallolmay,Greaney, Michael F.
supporting information; experimental part, p. 4946 - 4949 (2011/11/06)
Arynes, generated from trimethylsilyl phenyltriflate precursors, have been found to react with thioureas via a formal π-insertion into the C=S bond. The reaction contrasts with that of ureas, which proceeds via benzyne σ-insertion into the C-N bond, and r
