149099-14-9

Upstream product

• 170305-51-8 Methyl (2S,5S)-5-<(tert-Butyldiphenylsiloxy)methyl>tetrahydrofuran-2-carboxylate 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 201472-26-6 (2R/S,5S)-5-(tert-butyldiphenylsilyloxymethyl)tetrahydrofuran-2-ol 
• 313963-29-0 (S)-1-((tert-butyldiphenylsilyl)oxy)hex-5-en-2-ol 
• 106731-74-2 tert-butyl[(2S)-oxiran-2-ylmethoxy]diphenylsilane 
• 149099-13-8 (2S,5S)-5-([(1,1-dimethyl)ethyldiphenylsilyl]oxymethyl)tetrahydrofuran-2-carbonitrile 
• 201536-71-2 1-acetoxy-2,3-dideoxy-5-O-<(1,1-dimethylethyl)diphenylsilyl>-D-glycero-pentofuranose 
• 102717-29-3 (5S)-5-({[tert-butyl(diphenyl)silyl]oxy}methyl)dihydrofuran-2(3H)-one 
• 292069-13-7 (2S,5S)-2,5-di[(tert-butyldiphenylsilyl)oxymethyl]-2,5-dihydrofuran 
• 292069-07-9 (2S,5S)-2,5-di(trityloxymethyl)-2,5-dihydrofuran 
• 292069-11-5 (2S,5S)-2-[(tert-butyldiphenylsilyl)oxymethyl]-5-hydroxymethyl-2,5-dihydrofuran 
• 292069-09-1 (2S,5S)-2,5-di(hydroxymethyl)-2,5-dihydrofuran 
• 41107-82-8 2,5-anhydro-D-mannitol 
• 165876-55-1 (2S,5S)-5-<(tert-butyldiphenylsiloxy)methyl>tetrahydrofuran-2-methanol 

Downstream Products

• 165876-49-3 (2R,5R,2'S,5'S)-5-<5'-<(tert-butyldiphenylsiloxy)methyl>tetrahydro-2'-furyl>-1,2-O-isopropylidenepentane-1,2,5-triol 
• 149099-16-1 (2R,5S,2'S,5'S)-5-<5'-<(tert-Butyldiphenylsiloxy)methyl>tetrahydrofuran-2'-yl>-1,2-O-isopropylidenepentane-1,2,5-triol 
• 292069-02-4 (2S,3R,6S)-3-acetyl-6-[(tert-butyldiphenylsilyl)oxymethyl]-2-decyltetrahydropyran 
• 292069-16-0 (2S,5S)-2-[(tert-butyldiphenylsilyl)oxymethyl]-5-[(1'R)-(1'-hydroxy)decyl]tetrahydrofuran 
• 292069-20-6 (2S,5S)-5-[(1'R)-1'-acetoxydecyl]-2-[(tert-butyldiphenylsilyl)oxymethyl]tetrahydrofuran 
• 292069-22-8 Methanesulfonic acid (R)-1-[(2S,5S)-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-undecyl ester 
• 292069-24-0 Chloro-methanesulfonic acid (R)-1-[(2S,5S)-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-undecyl ester 
• 157732-26-8 (2S,5S,2'S,5'S)-5-<5'-<(tert-Butyldiphenylsiloxy)methyl>tetrahydrofuran-2'-yl>tetrahydrofuran-2-carboxaldehyde 
• 170553-09-0 (2R,5S,2'S,5'S)-5-<5'-<(tert-Butyldiphenylsiloxy)methyl>tetrahydrofuran-2'-yl>pentane-1,2,5-triol 
• 149099-19-4 (2S,5S,2'S,5'S,2''S,5''S)-5-<5'-<5''-<(tert-Butyldiphenylsiloxy)methyl>tetrahydrofuran-2''-yl>tetrahydrofuran-2'-yl>tetrahydrofuran-2-methanol 
• 149099-18-3 (2R,5S,2'S,5'S,2''S,5''S)-1,2-O-Isopropylidene-5-<5'-<5''-<(tert-butyldiphenylsiloxy)methyl>tetrahydrofuran-2''-yl>tetrahydrofuran-2'-yl>pentane-1,2,5-triol 

Relevant academic research and scientific papers

Total synthesis of (-)-goniotrionin

A stereoselective total synthesis of the reported structure of goniotrionin (4) has been accomplished. The key steps involved the opening of a chiral epoxide, a highly diastereoselective Mukaiyama aerobic oxidative cyclization, a selective 1,2-syn Mukaiyama aldol reaction, and a Noyori reduction.

Stereoselective synthesis of the 3-hydroxytetrahydropyran part of mucocin, an antitumor agent, based on rearrangement-ring expansion reaction of a tetrahydrofuran derivative

The synthesis of the 2,6-disubstituted 2,3-trans-3- hydroxytetrahydropyran part of mucocin, a potent antitumor agent, was accomplished based on the zinc acetate-induced ring expansion reaction of a tetrahydrofuran having a choloromethanesulfonate on the C

Stereoselective Synthesis of Oligo(tetrahydrofurans): Linear and Convergent Routes to Bi- and Tetrahydrofurans

The "dimeric" and "trimeric" oligo(tetrahydrofurans) (oligo-THFs) 24, 28, 32, and 38 were synthesized stereoselectively according to a linear and a convergent synthetic strategy.The oligo-THFs thus obtained are important intermediates for the synthesis of artificial ion channels.Furthermore, they can be used in the total synthesis of Annonaceae acetogenins, a class of natural occurring oligo-THFs with promising pharmacological properties. - Keywords: Synthesis, stereoselective / Oligo(tetrahydrofurans), natural, non-natural /Ion channels, artificial / Annonaceae acetogenins

Tetrahydrofuran-podands, stereoselective synthesis of trans-2,5-oligo-tetrahydrofurans

Enantiomerically pure THF-podands 1 were synthesized along a linear route starting from lactone 3. A high degree of stereochemical control was achieved by chelation controlled addition of the functionalized Grignard reagent 7 to α-alkoxy-aldehydes of type 6.