149108-73-6Relevant academic research and scientific papers
Palladium catalyzed cross-coupling reaction between 3-indole boronic acids and tetrahydropyridine triflates
Zheng, Qi,Yang, Youhua,Martin, Arnold R.
, p. 2235 - 2238 (1993)
The palladium catalyzed cross-coupling reaction between 3-indole boronic acids and vinyl triflates is a good method to introduce vinyl groups into the indole 3-position. The regioselectivity of the enolization of N-substituted-3-piperidones is far greater than previously reported. N-tosyl-3-indole boronic acids can be easily synthesized via mercuration-boronation method.
A CONVENIENT APPROACH TO THE N-SUBSTITUTED AMINO DIENES, N-BENZYL-5-ETHENYL-3,4-DIHYDROPYRIDIN-2-ONE AND N-CBZ-5-ETHENYL-1,2,3,4-TETRAHYDROPYRIDINE
Bigogno, Chiara,Danieli, Bruno,Lesma, Giordano,Passarella, Daniele
, p. 973 - 982 (2007/10/02)
A synthesis of N-substituted amino dienes (1a) and (1b) is described according to two different approaches. 1a is obtained trough condensation of methyl 4-formyl-6-selenophenylhexanoate (4) with benzylamine followed by oxidation and elimination; 1b is for
VINYLATION OF THE INDOLE 3-POSITION VIA PALLADIUM-CATALYZED CROSS-COUPLING
Zheng, Qi,Yang, Youhua,Martin, Arnold R.
, p. 1761 - 1772 (2007/10/02)
The palladium-catalyzed cross-coupling between 3-indoleboronic acids and vinyl triflates is an excellent method for the regioselective introduction of vinyl groups into the indole 3-position.The regioselectivity of the enolization of N-substituted 3-piperidones, as dictated by the nitrogen substituent, is far greater than previously reported.N-tosyl-3-indoleboronic acids can be easily synthesized using the mercuration-boronation methid.
