1492-11-1

Basic information

• Product Name: AC-LEU-OME
• Synonyms: AC-LEU-OME;AC-LEUCINE-OME;ACETYL-L-LEUCINE METHYL ESTER;N-ALPHA-ACETYL-L-LEUCINE METHYL ESTER;N-Acetyl-L-leucine methyl ester;Ac-L-Leu-OMe;(2S)-2-(Acetylamino)-4-methylpentanoic acid methyl ester;N-Acetylleucine methyl ester
• CAS NO: 1492-11-1
• Molecular Formula: C₉H₁₇NO₃
• Molecular Weight: 187.24
• Product Categories: Amino Acids
• Mol File: 1492-11-1.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 291.7 °C at 760 mmHg
• Flash Point: 130.2 °C
• Appearance: /
• Density: 0.999 g/cm³
• Storage Temp.: Store at RT.
• CAS DataBase Reference: AC-LEU-OME(CAS DataBase Reference)
• NIST Chemistry Reference: AC-LEU-OME(1492-11-1)
• EPA Substance Registry System: AC-LEU-OME(1492-11-1)

Safety Data

• Hazardous Substances Data: 1492-11-1(Hazardous Substances Data)

Usage

General Description

AC-LEU-OME is a synthetic chemical compound that is often used in research and development of pharmaceuticals and biotechnology. It is a modified peptide with the amino acid sequence acetyl-leucine-ornithine-methyl ester. AC-LEU-OME has been studied for its potential as a drug delivery system, as well as its antimicrobial and antifungal properties. AC-LEU-OME has also been investigated for its potential to act as an antioxidant and has shown promise in various biological and medical applications. Overall, this compound is of interest to the scientific community for its potential therapeutic benefits and further research is ongoing to explore its uses.

Upstream product

• 57289-25-5 methyl N-acetyl-leucinate 
• 6600-40-4 L-Norvaline 
• 67-56-1 methanol 
• 1188-21-2 N-Ac-Leu 
• 7517-19-3 methyl (L)-leucinate hydrochloride 
• 64-19-7 acetic acid 
• 108-24-7 acetic anhydride 
• 203873-66-9 (S)-methyl 4-methyl-2-(4-nitrophenylsulfonamido)pentanoate 
• 2666-93-5 (S)-Leu-OMe 
• 66299-18-1 Methyl (Z)-2-(iodoacetamido)-4-methylpent-2-enoate 
• 66299-17-0 Methyl (E)-2-(iodoacetamido)-4-methylpent-2-enoate 
• 63861-79-0 Methyl (Z)-2-(chloroacetamido)-4-methylpent-2-enoate 
• 63822-73-1 Methyl (E)-2-(chloroacetamido)-4-methylpent-2-enoate 
• 3682-43-7 4-methyl-2-oxo-pentanoic acid methyl ester 

Downstream Products

• 2666-93-5 (S)-Leu-OMe 
• 61-90-5 L-leucine 
• 28529-34-2 N-acetyl-L-leucine amide 
• 464-72-2 tetraphenylethane-1,2-diol 
• 32483-15-1 Ac-Leu-NHMe 

Relevant articles and documents

Engineering a polymeric chiral catalyst by using hydrogen bonding and coordination interactions

(Chemical Equation Presented) Noncovalent interactions are used to generate a polymeric supramolecular chiral catalyst (see picture). This heterogeneous catalyst, which is based on Feringa's MonoPhos/RhI system, is formed by orthogonal self-ass

The First Application of a Planar-Chiral Phosphorus Heterocycle in Asymmetric Catalysis: Enantioselective Hydrogenation of Dehydroamino Acids

-

Oxidative functionalization of aliphatic and aromatic amino acid derivatives with H2O2 catalyzed by a nonheme imine based iron complex

The oxidation of a series of N-acetyl amino acid methyl esters with H2O2 catalyzed by a very simple iminopyridine iron(ii) complex 1 easily obtainable in situ by self-assembly of 2-picolylaldehyde, 2-picolylamine, and Fe(OTf)2 was investigated. Oxidation of protected aliphatic amino acids occurs at the α-C-H bond exclusively (N-AcAlaOMe) or in competition with the side-chain functionalization (N-AcValOMe and N-AcLeuOMe). N-AcProOMe is smoothly and cleanly oxidized with high regioselectivity affording exclusively C-5 oxidation products. Remarkably, complex 1 is also able to catalyze the oxidation of the aromatic N-AcPheOMe. A marked preference for the aromatic ring hydroxylation over Cα-H and benzylic C-H oxidation was observed, leading to the clean formation of tyrosine and its phenolic isomers.

IMMUNOSTIMULATING AGENT

The present invention aims to provide an immunostimulating agent superior in an immunostimulatory effect, particularly a compound useful as a vaccine adjuvant, a pharmaceutical composition containing the compound, a vaccine containing the compound and an