149202-71-1Relevant academic research and scientific papers
v-Triazolines. Part 34. Thermal Behavior of 1-(2-Aminophenyl)-4,5-dihydro-5-morpholino-1,2,3-triazoles: New Synthesis of 2-Alkylquinoxalines
Battistini, Maurizio,Erba, Emanuela,Pocar, Donato
, p. 339 - 342 (2007/10/02)
4,5-Dihydro-5-morpholino-1-(2-nitrophenyl)-1,2,3-triazoles 4 are prepared by reaction of an aldehyde with morpholine and the appropriate aryl azide.On reduction 1-(2-aminophenyl)-4,5-dihydro-5-morpholino-1,2,3-triazoles 5 are formed.Thermal rearrangement of compounds 5 affords unstable 2-alkyl-3-amino-1,2,3,4-tetrahydroquinoxalines 7, which undergo deamination to 2-alkyl-1,2-dihydroquinoxalines 8.Oxidation of these affords 2-alkylquinoxalines 10.The mechanism of thermal the rearrangement of triazoles 5 is investigated and discussed.
