149204-99-9

Basic information

• Product Name: Fmoc-Gly-L-Phe-L-Leu-OtBu
• Synonyms: Fmoc-Gly-L-Phe-L-Leu-OtBu
• CAS NO: 149204-99-9
• Molecular Weight: 613.754
• Mol File: 149204-99-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Fmoc-Gly-L-Phe-L-Leu-OtBu(CAS DataBase Reference)
• NIST Chemistry Reference: Fmoc-Gly-L-Phe-L-Leu-OtBu(149204-99-9)
• EPA Substance Registry System: Fmoc-Gly-L-Phe-L-Leu-OtBu(149204-99-9)

Safety Data

• Hazardous Substances Data: 149204-99-9(Hazardous Substances Data)

Upstream product

• 28635-78-1 L-phenylalanyl-L-leucine tert-butyl ester 
• 84891-01-0 Fmoc-Phe-Leu-OtBu 
• 2748-02-9 L-leucine tert-butyl ester hydrochloride 
• 35661-40-6 N-Fmoc L-Phe 
• 86060-85-7 Fmoc-Gly-OPfp 
• 29022-11-5 N-(fluoren-9-ylmethoxycarbonyl)glycine 

Downstream Products

• 138372-38-0 Fmoc-Tyr(OBu^t)-Gly-Gly-Phe-Leu-OBu^t 
• 89137-25-7 (S)-2-((S)-2-{2-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)-acetylamino]-acetylamino}-3-phenyl-propionylamino)-4-methyl-pentanoic acid tert-butyl ester 
• 427881-22-9 (S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-tert-butoxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid tert-butyl ester 
• 77426-98-3 Gly-Gly-Phe-Leu-OBu^t 
• 81678-16-2 leucine enkephalin acetate 
• 82362-19-4 Gly-Phe-Leu(t-Bu) 

Relevant articles and documents

A new method for rapid solution synthesis of shorter peptides by use of PyBOP

By using PyBOP promoted coupling of Fmoc protected amino acids, and adopting the deprotection/washing procedure of the Fmoc Amino Acid Chloride Solution Technique (FAACST), a sample of [leucine5] enkephalin has been synthesized in a rapid, cont

Ynamides as Racemization-Free Coupling Reagents for Amide and Peptide Synthesis

A highly efficient, two-step, one-pot synthetic strategy for amides and peptides was developed by employing ynamides as novel coupling reagents under extremely mild reaction conditions. The ynamides not only are effective for simple amide and dipeptide synthesis but can also be used for peptide segment condensation. Importantly, no racemization was detected during the activation of chiral carboxylic acids. Excellent amidation selectivity toward amino groups in the presence of -OH, -SH, -CONH2, ArNH2, and the NH of indole was observed, making the protection of these functional groups unnecessary in amide and peptide synthesis.