81678-16-2

Basic information

• Product Name: LEUCINE ENKEPHALIN ACETATE SALT
• Synonyms: LEUCINE ENKEPHALIN ACETATE SALT;TYR-GLY-GLY-PHE-LEU ACETATE SALT;LEUCINE ENKEPHALIN SYNTHETIC ACETATE;(5-leucine)enkephalin acetate;Leucine Enkephalin hydrate acetate salt
• CAS NO: 81678-16-2
• Molecular Formula: C₂H₄O₂*C₂₈H₃₇N₅O₇
• Molecular Weight: 615.67
• Product Categories: EnkephalinsPeptides for Cell Biology;Enkephalins;Neuropeptides;Opioid Peptides
• Mol File: 81678-16-2.mol
• Article Data: 3

Chemical Properties

• Appearance: White/Lyophilized Powder
• Storage Temp.: −20°C
• CAS DataBase Reference: LEUCINE ENKEPHALIN ACETATE SALT(CAS DataBase Reference)
• NIST Chemistry Reference: LEUCINE ENKEPHALIN ACETATE SALT(81678-16-2)
• EPA Substance Registry System: LEUCINE ENKEPHALIN ACETATE SALT(81678-16-2)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 81678-16-2(Hazardous Substances Data)

Usage

Uses

[Leu5]-Enkephalin is a neurotransmitter used in molecular dynamics studies for the insertion of neurotransmitters into lipid bilayer membranes and their implication on membrane stability.

Upstream product

• 69729-16-4 N-benzyloxycarbonyl-L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucine benzyl ester 
• 64-19-7 acetic acid 
• 427881-22-9 (S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-tert-butoxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid tert-butyl ester 
• 61543-55-3 Z-Tyr-Gly-Gly hydrazide 
• 77066-56-9 benzyl-L-penylalanyl-L-leucinate trifluoroacetic acid 
• 35661-40-6 N-Fmoc L-Phe 
• 2748-02-9 L-leucine tert-butyl ester hydrochloride 
• 28635-78-1 L-phenylalanyl-L-leucine tert-butyl ester 
• 82362-19-4 Gly-Phe-Leu(t-Bu) 
• 77426-98-3 Gly-Gly-Phe-Leu-OBu^t 
• 138372-38-0 Fmoc-Tyr(OBu^t)-Gly-Gly-Phe-Leu-OBu^t 
• 89137-25-7 (S)-2-((S)-2-{2-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)-acetylamino]-acetylamino}-3-phenyl-propionylamino)-4-methyl-pentanoic acid tert-butyl ester 
• 149204-99-9 Fmoc-Gly-L-Phe-L-Leu-OtBu 
• 84891-01-0 Fmoc-Phe-Leu-OtBu 

Downstream Products

• 63-91-2 L-phenylalanine 
• 673-08-5 YG 
• 3303-55-7 L-Phe-Leu 
• 21778-69-8 tyrosylglycylglycine 
• 60-18-4 L-tyrosine 
• 60254-83-3 [des-tyr¹]-leucine enkephalin 

Relevant articles and documents

A RAPID NON-ACIDOLYTIC METHOD FOR DEPROTECTION AND REMOVAL OF PEPTIDES FROM SOLID PHASE RESINS - APPLICATIONS OF AMMONIUM FORMATE CATALYTIC TRANSFER HYDROGENATION

Ammonium formate aided catalytic transfer hydrogenation has been employed in the cleavage, and concommitant deprotection, of the pentapeptide leucine enkephalin from the Merrifield peptide resin under ambient conditions of temperature and pressure in a neutral medium.

NEW SYNTHESES OF LEU5-ENKEPHALIN AND ITS TYR4-ANALOG

-