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149209-48-3

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149209-48-3 Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 58, p. 2637, 1993 DOI: 10.1021/jo00061a048

Check Digit Verification of cas no

The CAS Registry Mumber 149209-48-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,2,0 and 9 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 149209-48:
(8*1)+(7*4)+(6*9)+(5*2)+(4*0)+(3*9)+(2*4)+(1*8)=143
143 % 10 = 3
So 149209-48-3 is a valid CAS Registry Number.

149209-48-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Iodo-6-(trifluoromethyl)phenol

1.2 Other means of identification

Product number -
Other names Phenol,2-iodo-6-(trifluoromethyl)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:149209-48-3 SDS

149209-48-3Relevant articles and documents

Discovery of isoxazole voltage gated sodium channel blockers for treatment of chronic pain

Shao, Pengcheng P.,Ye, Feng,Weber, Ann E.,Li, Xiaohua,Lyons, Kathryn A.,Parsons, William H.,Garcia, Maria L.,Priest, Birgit T.,Smith, McHardy M.,Felix, John P.,Williams, Brande S.,Kaczorowski, Gregory J.,McGowan, Erin,Abbadie, Catherine,Martin, William J.,McMasters, Daniel R.,Gao, Ying-Duo

scheme or table, p. 5334 - 5338 (2010/04/26)

A series of novel isoxazole voltage gated sodium channel blockers have been synthesized and evaluated. Substitutions on the benzylic position of benzamide were investigated to determine their effect on Nav1.7 inhibitory potency. The spirocyclobutyl substitution had the most significant enhancement on Nav1.7 inhibitory activity.

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