46377-35-9 Usage
Uses
Used in Pharmaceutical Industry:
2,6-Bis(trifluoromethyl)phenol is used as a key intermediate for the preparation of tebufelone analogs, which are a class of pharmaceutical compounds with potential applications in the treatment of various medical conditions. The trifluoromethyl groups in 2,6-Bis(trifluoroMethyl)phenol contribute to its enhanced lipophilicity and metabolic stability, making it a desirable component in the development of new drugs.
Additionally, due to its unique chemical structure, 2,6-Bis(trifluoromethyl)phenol can be further modified and used in the synthesis of other bioactive molecules, potentially expanding its applications in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 46377-35-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,6,3,7 and 7 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 46377-35:
(7*4)+(6*6)+(5*3)+(4*7)+(3*7)+(2*3)+(1*5)=139
139 % 10 = 9
So 46377-35-9 is a valid CAS Registry Number.
46377-35-9Relevant academic research and scientific papers
α-Oxygen-Substituted Organolithium Compounds and their Carbenoid Nature: Reactions with RLi and Other Nucleophiles, Experimental and IGLO-Calculated 13C-NMR Shifts of the Carbenoid C Atom
Boche, Gernot,Bosold, Ferdinand,Lohrenz, John C. W.,Opel, Achim,Zulauf, Peter
, p. 1873 - 1886 (2007/10/02)
In addition to the earlier demonstrated C-O bond elongation between the anionic carbon atom and oxygen in α-lithiated ethers which indicates a carbenoid character of these compounds we provide further evidence for this property in this publication.Thus, α
