149221-01-2

Upstream product

• 100-44-7 benzyl chloride 
• 10272-07-8 3.5-dimethoxyaniline 
• 149221-00-1 3,4-bis(methoxymethoxy)-N,N-diethyl-2-(3,5-dimethoxyphenylamino)benzamide 
• 1028276-02-9 C₁₆H₂₂O₈ 
• 149220-93-9 3,4-bis(methoxymethoxy)-N,N-diethylbenzamide 
• 1026327-50-3 methoxymethyl 3,4-bis(methoxymethoxy) benzoate 
• 149220-87-1 3,4-bis(methoxymethoxy)benzoic acid 
• 99-50-3 3,4-Dihydroxybenzoic acid 

Downstream Products

• 149220-91-7 5,6-dibenzyloxy-1,3-dimethoxy-9(10H)-acridone 
• 149221-02-3 5,6-dibenzyloxy-1-hydroxy-3-methoxy-10-methyl-9(10H)-acridone 
• 149220-99-5 5,6-dibenzyloxy-1,3-dimethoxy-10-methyl-9(10H)-acridine 

Relevant academic research and scientific papers

Syntheses of the acridone alkaloid citrusinine-I and its derivatives

Citrusinine-I (1), a naturally occurring acridone alkaloid with potent antiviral activity, was synthesized for the first time, via a route involving Ullmann reaction, cyclization, and selective demethylation at the 1-position with boron trifluoride etherate and lithium bromide. 1,5,6-Trihydroxy-3-methoxy-9(10H)-acridone (2a) and 1,5,6-trihydroxy-3-methoxy-10-methyl-9(10H)-acridone (2b) were also synthesized.