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14923-17-2

14923-17-2

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14923-17-2 Usage

Uses

Arcaine sulfate is a novel and potent antagonist of the polyamine site on the NMDA receptor.

Biological Activity

NO synthase inhibitor. An NMDA antagonist acting as a competitive inhibitor at the polyamine site.

Check Digit Verification of cas no

The CAS Registry Mumber 14923-17-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,9,2 and 3 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 14923-17:
(7*1)+(6*4)+(5*9)+(4*2)+(3*3)+(2*1)+(1*7)=102
102 % 10 = 2
So 14923-17-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H16N6.H2O4S/c7-5(8)11-3-1-2-4-12-6(9)10;1-5(2,3)4/h1-4H2,(H4,7,8,11)(H4,9,10,12);(H2,1,2,3,4)

14923-17-2 Well-known Company Product Price

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  • Sigma

  • (A0384)  Arcainesulfatesalt  

  • 14923-17-2

  • A0384-50MG

  • 1,244.88CNY

  • Detail

14923-17-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name Arcaine sulfate,N,N'-1,4-Butanediylbisguanidinesulfate

1.2 Other means of identification

Product number -
Other names Butane-1,4-diguanidium sulfate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:14923-17-2 SDS

14923-17-2Downstream Products

14923-17-2Relevant articles and documents

Synthesis and pharmacology of alkanediguanidinium compounds that block the neuronal nicotinic acetylcholine receptor

Villarroya, Mercedes,Gandia, Luis,Lopez, Manuela G.,Garcia, Antonio G.,Cueto, Senida,Garcia-Navio, Jose-Luis,Alvarez-Builla, Julio

, p. 1177 - 1183 (1996)

Taking as models the polyamine toxin fraction FTX from the funnel-web spider venom, and the guanidinium moiety of guanethidine, a series of azaalkane-1,ω-diguanidinium salts were obtained. Some of them blocked ion fluxes through the neuronal nicotinic receptors for acetylcholine (nAChR). The blockade was exerted at submicromolar concentrations, suggesting a highly selective interaction with the nAChR. In fact, the active compounds on the nAChR ion channel did not recognize the voltage-dependent Na+ or Ca2+ channels of bovine adrenal chromaffin cells. Therefore, these compounds may be useful tools to clarify the functions of nAChR receptors in the central and peripheral nervous systems.

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