14928-77-9Relevant academic research and scientific papers
Efficient DBU accelerated synthesis of 18F-labelled trifluoroacetamides
Gómez, Antonio Bermejo,Cortés González, Miguel A.,Lübcke, Marvin,Johansson, Magnus J.,Halldin, Christer,Szabó, Kálmán J.,Schou, Magnus
supporting information, p. 13963 - 13966 (2016/12/09)
Nucleophilic 18F-fluorination of bromodifluoromethyl derivatives was performed using [18F]Bu4NF in the presence of DBU (1,8-diazabicyclo[5.4.0]undec-7-ene). This novel procedure provided a diverse set of [18F]trifluoroacetamides in good to excellent radiochemical conversions. A mechanism where DBU acts as organomediator in this transformation is proposed.
Reductive amination without an external hydrogen source
Chusov, Denis,List, Benjamin
supporting information, p. 5199 - 5201 (2014/05/20)
A method of reductive amination without an external hydrogen source is reported. Carbon monoxide is used as the reductant. The reaction proceeds efficiently for a variety of carbonyl compounds and amines at low catalyst loadings and is mechanistically interesting as it does not seem to involve molecular hydrogen. Look, no H2! Reductive amination without an external hydrogen source has been developed using carbon monoxide as the reductant and rhodium acetate (0.2-1mol %) as catalyst. The method tolerates a variety of functional groups and provides target amines in good to excellent yields.
One-Step Hydroamidation of a Schiff Base with Trichlorosilane
Okamoto, Hidenori,Kato, Shozo
, p. 2128 - 2130 (2007/10/02)
We have found that the treatment of a Schiff base (2) with trichlorosilane and chloroacetyl chloride results in a highly active chloroacetamide herbicide (1) in an excellent yield .This one-step hydroamidation reaction of a Schiff base is a useful synthet
