149312-20-9Relevant academic research and scientific papers
Synthesis of 1,5-Anhydro-D-fructose derivatives and evaluation of their inflammasome inhibitors
Goto, Kohtaro,Ideo, Hiroko,Tsuchida, Akiko,Hirose, Yuriko,Maruyama, Ikuro,Noma, Satoshi,Shirai, Takashi,Amano, Junko,Mizuno, Mamoru,Matsuda, Akio
, p. 3763 - 3772 (2018)
Synthesis of several 1,5-Anhydro-D-fructose (1,5-AF) derivatives to evaluate inhibitory activities of the inflammasome was carried out. Recently, 1,5-AF reported to suppress the inflammasome, although with only low activity. We focused on the hydration of
Anomeric effect on kinetic acidity: Examples for the oxygen atom of ethers to accelerate abstraction of an α-hydrogen atom
Sakakibara, Tohru,Ito, Shinji,Ikegawa, Hiroshi,Matsuo, Ichiro,Seta, Akinori
, p. 3429 - 3432 (2007/10/02)
In contrast with general observation, two different types of experiments indicate that the abstraction of α-hydrogen atom of ether having proper conformation is slightly enhanced by the oxygen atom in line with our previous AM1 calculation.
