149355-52-2 Usage
General Description
7-Cyano-1,2,3,4-tetrahydroisoquinoline is a chemical compound with the molecular formula C11H11N. It is a heterocyclic compound that contains a tetrahydroisoquinoline ring system with a cyano (CN) functional group attached at the seventh position. 7-CYANO-1,2,3,4-TETRAHYDROISOQUINOLINE is used in organic synthesis and medicinal chemistry, and it has potential pharmaceutical applications due to its biological activity, such as its ability to act as a dopamine receptor antagonist. Additionally, 7-cyano-1,2,3,4-tetrahydroisoquinoline has been studied for its potential as a building block in the synthesis of various bioactive molecules and as a ligand in coordination chemistry. Its structure and properties make it a valuable compound for further research and development in the fields of drug discovery and chemical biology.
Check Digit Verification of cas no
The CAS Registry Mumber 149355-52-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,3,5 and 5 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 149355-52:
(8*1)+(7*4)+(6*9)+(5*3)+(4*5)+(3*5)+(2*5)+(1*2)=152
152 % 10 = 2
So 149355-52-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H10N2/c11-6-8-1-2-9-3-4-12-7-10(9)5-8/h1-2,5,12H,3-4,7H2
149355-52-2Relevant articles and documents
NOVEL TETRAHYDROISOQUINOLINES AND TERAHYDRONAPHTHYRIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION
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Page/Page column 49, (2018/05/24)
The present invention provides novel compounds having the general formula (I): wherein R1, R 2, R 3, U, V, W, X and Y are as described herein, compositions including the compounds and methods of using the compounds.
Examination of the role of the acidic hydrogen in imparting selectivity of 7-(aminosulfonyl)-1,2,3,4-tetrahydroisoquinoline (SK and F 29661) toward inhibition of phenylethanolamine N-methyltransferase vs the α2-adrenoceptor
Grunewald, Gary L.,Dahanukar, Vilas H.,Caldwell, Timothy M.,Criscione, Kevin R.
, p. 3997 - 4005 (2007/10/03)
7-(Aminosulfonyl)-1,2,3,4-tetrahydroisoquinoline (SK and F 29661, 1) is a potent inhibitor of the enzyme phenylethanolamine N-methyltransferase (PNMT, EC 2.1.1.28). In contrast to other inhibitors of PNMT, it is also highly selective toward PNMT in compar