200137-82-2

Basic information

• Product Name: 2-Trityl-1,2,3,4-tetrahydro-isoquinoline-7-carbonitrile
• Synonyms: 2-Trityl-1,2,3,4-tetrahydro-isoquinoline-7-carbonitrile
• CAS NO: 200137-82-2
• Molecular Weight: 400.523
• Mol File: 200137-82-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Trityl-1,2,3,4-tetrahydro-isoquinoline-7-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Trityl-1,2,3,4-tetrahydro-isoquinoline-7-carbonitrile(200137-82-2)
• EPA Substance Registry System: 2-Trityl-1,2,3,4-tetrahydro-isoquinoline-7-carbonitrile(200137-82-2)

Safety Data

• Hazardous Substances Data: 200137-82-2(Hazardous Substances Data)

Upstream product

• 76-83-5 trityl chloride 
• 149355-52-2 7-cyano-1,2,3,4-tetrahydroisoquinoline 
• 72299-68-4 1,2,3,4-Tetrahydro-isoquinolin-7-ylamine 
• 99365-69-2 7-nitro-1,2,3,4-tetrahydroisoquinoline hydrochloride 

Downstream Products

• 200137-84-4 N-(2-Trityl-1,2,3,4-tetrahydro-isoquinolin-7-ylmethyl)-methanesulfonamide 
• 200137-83-3 C-(2-Trityl-1,2,3,4-tetrahydro-isoquinolin-7-yl)-methylamine 

Relevant articles and documents

Examination of the role of the acidic hydrogen in imparting selectivity of 7-(aminosulfonyl)-1,2,3,4-tetrahydroisoquinoline (SK and F 29661) toward inhibition of phenylethanolamine N-methyltransferase vs the α2-adrenoceptor

7-(Aminosulfonyl)-1,2,3,4-tetrahydroisoquinoline (SK and F 29661, 1) is a potent inhibitor of the enzyme phenylethanolamine N-methyltransferase (PNMT, EC 2.1.1.28). In contrast to other inhibitors of PNMT, it is also highly selective toward PNMT in compar