200137-84-4

Basic information

• Product Name: N-(2-Trityl-1,2,3,4-tetrahydro-isoquinolin-7-ylmethyl)-methanesulfonamide
• Synonyms: N-(2-Trityl-1,2,3,4-tetrahydro-isoquinolin-7-ylmethyl)-methanesulfonamide
• CAS NO: 200137-84-4
• Molecular Weight: 482.646
• Mol File: 200137-84-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2-Trityl-1,2,3,4-tetrahydro-isoquinolin-7-ylmethyl)-methanesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-Trityl-1,2,3,4-tetrahydro-isoquinolin-7-ylmethyl)-methanesulfonamide(200137-84-4)
• EPA Substance Registry System: N-(2-Trityl-1,2,3,4-tetrahydro-isoquinolin-7-ylmethyl)-methanesulfonamide(200137-84-4)

Safety Data

• Hazardous Substances Data: 200137-84-4(Hazardous Substances Data)

Upstream product

• 149355-52-2 7-cyano-1,2,3,4-tetrahydroisoquinoline 
• 99365-69-2 7-nitro-1,2,3,4-tetrahydroisoquinoline hydrochloride 
• 72299-68-4 1,2,3,4-Tetrahydro-isoquinolin-7-ylamine 
• 124-63-0 methanesulfonyl chloride 
• 200137-83-3 C-(2-Trityl-1,2,3,4-tetrahydro-isoquinolin-7-yl)-methylamine 
• 200137-82-2 2-Trityl-1,2,3,4-tetrahydro-isoquinoline-7-carbonitrile 

Relevant articles and documents

Examination of the role of the acidic hydrogen in imparting selectivity of 7-(aminosulfonyl)-1,2,3,4-tetrahydroisoquinoline (SK and F 29661) toward inhibition of phenylethanolamine N-methyltransferase vs the α2-adrenoceptor

7-(Aminosulfonyl)-1,2,3,4-tetrahydroisoquinoline (SK and F 29661, 1) is a potent inhibitor of the enzyme phenylethanolamine N-methyltransferase (PNMT, EC 2.1.1.28). In contrast to other inhibitors of PNMT, it is also highly selective toward PNMT in compar