149358-58-7Relevant articles and documents
Evidence against an Alternative Mechanism for a Self-Replicating System
Wintner, Edward A.,Tsao, Belinda,Rebek, Julius
, p. 7997 - 8001 (1995)
A recent paper by Menger et al. described experimental and computational work related to our self-replicating system and concluded that amide catalysis - either external or internal - is the cause of observed rate enhancements.Herein we show that the proporsal of Menger et al. is inconsistent with published data, that their conclusions overreach the data afforded by their experiments, and that the step which they modeled is likely irrelevant to the autocatalytic nature of the system.We present new results and a refined mechanism in which the transition state is stabilized not by amides but by template-based recognition, the hallmark of self-replicating systems.
Homoleptic Bis(trimethylsilyl)amides of Yttrium Complexes Catalyzed Hydroboration Reduction of Amides to Amines
Ye, Pengqing,Shao, Yinlin,Ye, Xuanzeng,Zhang, Fangjun,Li, Renhao,Sun, Jiani,Xu, Beihang,Chen, Jiuxi
supporting information, p. 1306 - 1310 (2020/02/22)
Homoleptic lanthanide complex Y[N(TMS)2]3 is an efficient homogeneous catalyst for the hydroboration reduction of secondary amides and tertiary amides to corresponding amines. A series of amides containing different functional groups such as cyano, nitro, and vinyl groups were found to be well-tolerated. This transformation has also been nicely applied to the synthesis of indoles and piribedil. Detailed isotopic labeling experiments, control experiments, and kinetic studies provided cumulative evidence to elucidate the reaction mechanism.
Nickel-catalyzed reductive amidation of aryl-triazine ethers
Heravi, Majid M.,Panahi, Farhad,Iranpoor, Nasser
supporting information, p. 1992 - 1995 (2020/02/22)
The reaction of activated phenolic compounds, 2,4,6-triaryloxy-1,3,5-triazine (aryl-triazine ethers), with various isocyanates or carbodiimides in the presence of a nickel pre-catalyst resulted in the synthesis of aryl amides in good to excellent yields.
