149379-78-2Relevant academic research and scientific papers
A Simple Synthesis of 2-Methoxypyridine-3-carbonitriles
Victory, Pedro,Borrell, Jose I.,Vidal-Ferran, Anton
, p. 769 - 776 (2007/10/02)
The condensation of propanedinitrile with several enals or enones in a methanol-sodium methoxide system provides a one-step route to 2-methoxypyridine-3-carbonitriles.Together with these compounds substituted 2-aminobenzene-1,3-dicarbonitriles, were obtained as by-products.
SYNTHESIS OF 4-AMINO-8-CYANOQUINAZOLINES FROM ENONES AND ENALS
Victory, Pedro,Borrell, Jose I.,Vidal-Ferran, Anton,Montenegro, Elvira,Jimeno, M. Luisa
, p. 2273 - 2280 (2007/10/02)
The treatment in a sodium methoxide/methanol solution of α,β-unsaturated enones or aldehydes with propanedinitrile in a 1:2 molar ratio led to 2-aminobenzene-1,3-dicarbonitriles.These compounds afforded 4-amino-8-cyanoquinazolines by reaction with formamide or guanidine.
