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1-(4-BROMOPHENYL)-4-1H-IMIDAZOL-1-YL-BUTANONE, also known as 4-BPIB, is a chemical compound belonging to the imidazole derivatives group. It is characterized by its potential as an enzyme and receptor inhibitor, particularly in neuroscience research and drug discovery. 4-BPIB has demonstrated anti-inflammatory and antitumor properties, making it a promising candidate for therapeutic applications in conditions such as Alzheimer's disease and cancer. Its capacity to modulate neurotransmitter release also positions it as a valuable tool for studying the central nervous system. Given its diverse biological activities, 4-BPIB is a molecule of significant interest for further research and potential drug development.

149490-78-8

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149490-78-8 Usage

Uses

Used in Pharmaceutical Research and Drug Discovery:
4-BPIB is used as an enzyme and receptor inhibitor for [application reason] in the field of neuroscience. Its ability to modulate the release of neurotransmitters makes it a valuable tool for studying the central nervous system and contributes to the development of new therapeutic agents.
Used in Neuroscience Applications:
In the field of neuroscience, 4-BPIB is used as a research compound for [application reason] to investigate its potential in treating neurological disorders and understanding the mechanisms of neurotransmission.
Used in Anti-inflammatory Applications:
4-BPIB is used as an anti-inflammatory agent for [application reason] to alleviate inflammation and potentially treat conditions associated with inflammatory processes.
Used in Antitumor Applications:
In oncology, 4-BPIB is used as an antitumor agent for [application reason] to inhibit tumor growth and progression, offering a potential therapeutic strategy for cancer treatment.
Used in Alzheimer's Disease Research:
4-BPIB is used as a therapeutic agent for [application reason] in Alzheimer's disease research, exploring its potential to mitigate cognitive decline and neurodegeneration associated with the condition.
Used in Cancer Research and Treatment:
4-BPIB is used as a potential cancer treatment for [application reason] in cancer research, targeting specific enzymes and receptors that contribute to tumor development and growth.

Check Digit Verification of cas no

The CAS Registry Mumber 149490-78-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,4,9 and 0 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 149490-78:
(8*1)+(7*4)+(6*9)+(5*4)+(4*9)+(3*0)+(2*7)+(1*8)=168
168 % 10 = 8
So 149490-78-8 is a valid CAS Registry Number.
InChI:InChI=1/C13H13BrN2O/c14-12-5-3-11(4-6-12)13(17)2-1-8-16-9-7-15-10-16/h3-7,9-10H,1-2,8H2

149490-78-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(4-bromophenyl)-4-imidazol-1-ylbutan-1-one

1.2 Other means of identification

Product number -
Other names OR1653

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:149490-78-8 SDS

149490-78-8Relevant academic research and scientific papers

Synthesis of 1-aryl-4-azolylbutanones

Karachev,Popkov

, p. 987 - 993 (2007/10/03)

A convenient method was developed for the synthesis of substituted 4-azolyl-1-arylbutanones from the available γ-chlorobutyrophenones by successive stages of transformation into ketals, alkylation of sodium imidazolate or 1,2,4-triazolate by the ketals in

Reaction of Aromatic Ketones with 3-Mercapto-1,2-propanediol. Synthesis of cis- and trans-2-Alkyl-2-aryl-(1,3-oxathiolane-5-methanols and 1,3-dioxolane-4-methanethiols)

Upadhyaya, Subhash,Bauer, Ludwig

, p. 1053 - 1065 (2007/10/02)

Aromatic ketones react with 3-mercapto-1,2-propanediol (1) in refluxing benzene under the catalytic influence of sulfonic acid and with azeotropic removal of water to yield a mixture comprised predominantly of cis- and trans-2-alkyl-2-aryl-1,3-oxathiolane

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