82117-19-9

Basic information

• Product Name: 2-(4-bromophenyl)-2-(3-chloropropyl)-1,3-dioxolane
• CAS NO: 82117-19-9
• Molecular Formula: C₁₂H₁₄BrClO₂
• Molecular Weight: 305.5954
• Mol File: 82117-19-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 364.9°C at 760 mmHg
• Flash Point: 174.5°C
• Density: 1.42g/cm³
• Vapor Pressure: 3.43E-05mmHg at 25°C
• Refractive Index: 1.544
• CAS DataBase Reference: 2-(4-bromophenyl)-2-(3-chloropropyl)-1,3-dioxolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-bromophenyl)-2-(3-chloropropyl)-1,3-dioxolane(82117-19-9)
• EPA Substance Registry System: 2-(4-bromophenyl)-2-(3-chloropropyl)-1,3-dioxolane(82117-19-9)

Safety Data

• Hazardous Substances Data: 82117-19-9(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Common uses

Pharmaceutical intermediate, organic synthesis

Known for

Versatile chemical properties, production of various drugs and pharmaceuticals

Reagent in

Synthesis of complex organic molecules

Key building block in

Development of new chemical compounds

Potential properties

Medicinal and pharmacological

Upstream product

• 107-21-1 ethylene glycol 
• 4559-96-0 1-(4-bromophenyl)-4-chlorobutan-1-one 
• 108-86-1 bromobenzene 

Downstream Products

• 149490-78-8 1-(4-bromophenyl)-4-(1H-imidazol-1-yl)-1-butanone 

Relevant articles and documents

The synthesis of ω-(2-aryl-1,3-dioxolan-2-yl)alkyl purine derivatives and their activity towards HIV reverse transcriptase

Novel derivatives of 6-substituted purines were synthesized by alkylation of 6-substituted purines with various 2-(chloroalkyl)-2-aryl-1,3-dioxolanes and related compounds. Their inhibitory properties toward HIV reverse transcriptase were studied. The structure-activity relationship within the synthesized compounds was found.

NPY antagonists: spiroisoquinolinone derivatives

A series of non-peptidergic antagonists of NPY have been synthesized and are comprised of spiroisoquinolinone derivatives of Formula I. As antagonists of NPY-induced feeding behavior, these compounds and known analogs are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.