149564-35-2Relevant academic research and scientific papers
Synthesis of trans-fused octahydroisoindole-1-carboxylic acids
Laborda, Pedro,Sayago, Francisco J.,Cativiela, Carlos,Gotor, Vicente
, p. 404 - 411 (2018/05/22)
trans-Fused octahydroisoindole-1-carboxylic acids are bicyclic proline analogues of potential interest in the search for new drugs. Within this work, the trans-fused octahydroisoindole system has been constructed using methyl trans-2-(hydroxymethyl)cycloh
Towards the synthesis of HIV-protease inhibitors. Synthesis optically pure 3-carboxyl-decahydroisoquinolines
Houpis, Ioannis N.,Molina, Audrey,Reamer, Robert A.,Lynch, Joseph E.,Volante,Reider, Paul J.
, p. 2593 - 2596 (2007/10/02)
The synthesis of optically pure decahydroisoquinoline 1, a component of HIV-protease inhibitors, was accomplished in 30-33% overall yield from the readily available optically pure monoacid 4.
