14959-71-8Relevant academic research and scientific papers
Oxidative Rearrangement of 3-Aminoindazoles for the Construction of 1,2,3-Benzotriazine-4(3 H)-ones at Ambient Temperature
Zhou, Yao,Wang, Ya,Lou, Yixian,Song, Qiuling
, p. 6494 - 6497 (2018)
A novel oxidative rearrangement of 3-aminoindazoles is reported, enabling the production of diverse functionalized 1,2,3-benzotriazine-4(3H)-ones in good yields at room temperature. The key success of this unprecedented transformation of 3-aminoindazoles is the use of water as cosolvent, which could facilitate the halogen-induced ring expansion of 3-aminoindazoles under oxidative conditions.
Transition metal-free cascade reactions of alkynols to afford isoquinolin-1(2H)-one and dihydroisobenzofuran derivatives
Li, Deng Yuan,Shi, Ke Ji,Mao, Xiao Feng,Chen, Guo Rong,Liu, Pei Nian
, p. 4602 - 4614 (2014/06/09)
Transition metal-free cascade reactions of alkynols with imines have been achieved using potassium tert-butoxide as catalyst. Switching the reaction solvent gives two kinds of products in good yield: isoquinolin-1(2H)-one derivatives and dihydroisobenzofuran derivatives. This approach was used to generate the natural product 8-oxypseudopalmatine in a two-step procedure from commercially available starting materials. Additionally, multicomponent reactions of alkynols, aldehydes, and amines were also successfully achieved to afford isoquinolin-1(2H)-one derivatives.
The preparation of substituted 1(2H)-isoquinolinones from dilithiated 2- methyl-N-arylbenzamides, 2-methyl-N-(arylmethyl)-benzamides, or 2- methylbenzoic acid, 2,2-dimethylhydrazide
Davis, Sharon E.,Church, A. Cameron,Griffith, Cynthia L.,Beam, Charles F.
, p. 2961 - 2969 (2007/10/03)
2-Methyl-N-arylbenzamides (N-aryl-ortho-toluamides), 2-methyl-N- (arylmethyl)-benzamides (substituted benzyl, N-benzyl-ortho-toluamides), or 2-methylbenzoic acid, 2,2-dimethylhydrazide (ortho-toluic acid, N,N- dimethylhydrazide), were dilithiated with exc
