1496-02-2

Basic information

• Product Name: p-Fluorobenzoic acid 2-phenylhydrazide
• Synonyms: p-Fluorobenzoic acid 2-phenylhydrazide;p-Fluoro-N'-phenylbenzhydrazide
• CAS NO: 1496-02-2
• Molecular Formula: C₁₃H₁₁FN₂O
• Molecular Weight: 230.2376432
• Mol File: 1496-02-2.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 325.2°C at 760 mmHg
• Flash Point: 150.5°C
• Appearance: /
• Density: 1.269g/cm³
• Vapor Pressure: 0.000233mmHg at 25°C
• Refractive Index: 1.628
• CAS DataBase Reference: p-Fluorobenzoic acid 2-phenylhydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: p-Fluorobenzoic acid 2-phenylhydrazide(1496-02-2)
• EPA Substance Registry System: p-Fluorobenzoic acid 2-phenylhydrazide(1496-02-2)

Safety Data

• Hazardous Substances Data: 1496-02-2(Hazardous Substances Data)

Usage

Uses

Agricultural chemical.

Hazard

A poison by ingestion.

InChI:InChI=1/C13H11FN2O/c14-11-8-6-10(7-9-11)13(17)16-15-12-4-2-1-3-5-12/h1-9,15H,(H,16,17)

Upstream product

• 403-43-0 4-fluorobenzoyl chloride 
• 100-63-0 phenylhydrazine 
• 83844-91-1 (4-Fluoro-phenyl)-phenylazo-methyl-hydroperoxide 

Downstream Products

• 25939-02-0 4-fluoro-N'-phenylbenzohydrazonoyl chloride 
• 1515829-92-1 4-Fluoro-N′-(2-nitrophenyl)-N′-phenylbenzohydrazide 
• 1515830-40-6 3-(4-fluorophenyl)-1-phenyl-1,4-dihydro-1,2,4-benzotriazin-4-yl 
• 918497-03-7 (Z)-4-fluoro-N-phenylbenzohydrazonyl chloride 
• 1419258-69-7 3-(4-fluoro-phenyl)-1,5-diphenyl-4,5-dihydro-1H-pyrazole-4-carboxylic acid (5-hydroxy-4,4-dimethyl-pentyl)-amide 
• 1419259-09-8 C₂₂H₁₇FN₂O₂ 
• 1419259-02-1 C₂₀H₂₁FN₂O₂ 
• 1419259-07-6 C₂₃H₁₉FN₂O₂ 
• 1419259-00-9 C₂₂H₂₅FN₂O₂ 

Relevant articles and documents

Intramolecular Diels-Alder and [3+2] Cycloaddition Reactions in the One-Pot Synthesis of Epoxypyrrolo[3,4-g]indazoles

A one-pot approach for the synthesis of epoxypyrrolo[3,4- g ]indazoles is presented. The first step was initiated by a three-component reaction of an isocyanide, a dialkyl acetylenedicarboxylate, and 2-furancarboxylic acid, and led to 1,3-dioxoepoxyisoindole, followed by the addition of hydrazonoyl chloride through a [3+2]-cycloaddition reaction in the second step. The key step in the formation of final compound involves a bicyclization strategy through intramolecular Diels-Alder (IMDA) reaction.

Copper-Catalyzed Tandem Dehydrocyanation and [3+2] Cyclo-addition Reactions of Phenacylmalononitriles: Regioselective Synthesis of Functionalized 4-Benzoyl-5-cyanopyrazoles under Mild Conditions

A novel copper-catalyzed [3+2] cycloaddition reaction with concomitant in situ generation of benzoylacrylonitriles and nitrile imines from phenacylmalononitriles and hydrazonoyl chlorides, respectively, is reported. The reaction was performed using copper(I) chloride as catalyst and N-methylimidazole as a clean complexing agent/weak base to afford the functionalized 4-benzoyl-5-cyanopyrazoles in moderate to good yields and excellent regioselectivity under ambient conditions. This method provides rapid access to a wide range of highly functionalized 4-benzoyl-5-cyanopyrazoles.

A [4 + 3] Annulation Reaction of aza- o-Quinone Methides with Arylcarbohydrazonoyl Chlorides for Synthesis of 2,3-Dihydro-1 H-benzo[ e][1,2,4]triazepines

An unprecedented [4 + 3] annulation reaction of aza-ortho-quinone methides with arylcarbohydrazonoyl chlorides has been achieved under mild conditions. The annulation underwent a sequential conjugate addition/intramolecular annulation/rearrangement, providing a useful method for the synthesis of biologically interesting 2,3-dihydro-1H-benzo[e][1,2,4]triazepine.