1496-35-1 Usage
General Description
1-(3-Fluorophenyl)cyclohexanol is a chemical compound that belongs to the class of cyclohexanols, which are cyclic alcohols. It is also known as fluorocyclohexanol and is derived from a cyclohexane ring with a fluorophenyl group attached to one of its carbon atoms. 1-(3-Fluorophenyl)cyclohexanol has potential applications in the pharmaceutical and agrochemical industries, as well as in the production of synthetic organic compounds. It is often used as a building block in the synthesis of various medicinal and agricultural products due to its unique chemical structure and properties. Additionally, 1-(3-Fluorophenyl)cyclohexanol may have certain biological activities that make it a subject of scientific research for potential therapeutic uses. Overall, this chemical compound has significant potential for various industrial and scientific applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1496-35-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,9 and 6 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1496-35:
(6*1)+(5*4)+(4*9)+(3*6)+(2*3)+(1*5)=91
91 % 10 = 1
So 1496-35-1 is a valid CAS Registry Number.
1496-35-1Relevant articles and documents
The Barbier-Grignard-Type Arylation of Ketones and Unexpected Cross-Coupling of Phenolic Ketones using Unactivated Aryl Bromides
Wen, Yunming,Chen, Guifang,Huang, Shiqiang,Tang, Yu,Yang, Jun,Zhang, Yuanming
, p. 947 - 957 (2016/04/05)
A novel, highly versatile and efficient method has been developed for the Barbier-Grignard-type arylation of ketones and an unexpected cross-coupling of phenolic ketones was observed using unactivated bromides and magnesium in tetrahydrofuran/toluene at 96°C promoted by multicatalysts of cupric bromide (15 mol%), bismuth chloride (5 mol%) and silver bromide (10 mol%). The substituent and electronic effects on the reaction have been discussed. High yields of arylation and cross-coupling have been attained under mild conditions. A novel reasonable mechanism involving a quinone intermediate is proposed. The high chemical selectivity in the cross-coupling to the hydroxy group of phenolic ketones should help ketones find new applications.
