14960-90-8

Usage

Uses

Used in Pharmaceutical Research:
1-(4-BROMO-PHENYL)-4-PHENYL-PIPERAZINE is used as a precursor or intermediate for the synthesis of various drugs, particularly those targeting the central nervous system. Its role in drug development is significant, as it can be modified to improve the therapeutic applications and effectiveness of the resulting compounds.
Used in Organic Chemistry:
In the field of organic chemistry, 1-(4-BROMO-PHENYL)-4-PHENYL-PIPERAZINE serves as a building block for creating new compounds with potential applications in various industries. Its versatility and the ability to alter its properties make it a subject of interest for researchers and chemists working on innovative chemical solutions.

InChI:InChI=1/C16H17BrN2/c17-14-6-8-16(9-7-14)19-12-10-18(11-13-19)15-4-2-1-3-5-15/h1-9H,10-13H2

Upstream product

• 106-40-1 4-bromo-aniline 
• 553-27-5 aniline mustard 
• 92-54-6 4-phenyl-1-piperazine 
• 106-37-6 1.4-dibromobenzene 

Downstream Products

• 156464-89-0 diethyl 4-(4-phenylpiperazinyl)phenylphosphonate 
• 173976-02-8 4-(4-phenyl-piperazin-1-yl)benzonitrile 

Relevant academic research and scientific papers

Synthesis of some new distyrylbenzene derivatives using immobilized Pd on an NHC-functionalized MIL-101(Cr) catalyst: photophysical property evaluation, DFT and TD-DFT calculations

In this study the catalytic application of a heterogeneous Pd-catalyst system based on metal organic framework [Pd-NHC-MIL-101(Cr)] was investigated in the synthesis of distyrylbenzene derivatives using the Heck reaction. The Pd-NHC-MIL-101(Cr) catalyst s

Chromophore structure, second harmonic generation, and orientational order in zirconium phosphonate/phosphate self-assembled multilayers

Two new phosphonate-terminated polar azo dyes, one that is substantially rigid (1) and the other with a large molecular hyperpolarizability (2), were designed and incorporated into zirconium-based surface multilayers. Second harmonic generation (SHG) was observed from the multilayers as a function of incident and polarization angles and compared with that from the previously reported aminophenylazophenylphosphonic acid chromophore 3. The new dyes are analogous to moieties commonly used in electric field-poled polymers, allowing comparisons between the polymers and the multilayers. Apparent order parameters (cos3θ) are >0.2 for 1 and ?0.16 for 2. Because of local field effects, the value for 1 is probably a lower limit. Use of other dyes that are both rigid and highly polar led to H-aggregation. Insertion of a nonpolar chromophore layer among the polar layers had no effect on SHG. The syntheses involved several novel reactions, involving the preparation of an unsymmetrically substituted diphenylpiperazine, an anilinoalkyl phosphonate, and the deprotected phosphonic acids themselves.