149690-13-1

Basic information

• Product Name: ethyl (2S,4S)-4-amino-5-[(1,1'-biphenyl)-4-yl]-2-methylpentanoate hydrochloride
• Synonyms: ethyl (2S,4S)-4-amino-5-[(1,1'-biphenyl)-4-yl]-2-methylpentanoate hydrochloride
• CAS NO: 149690-13-1
• Molecular Weight: 347.885
• Mol File: 149690-13-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl (2S,4S)-4-amino-5-[(1,1'-biphenyl)-4-yl]-2-methylpentanoate hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (2S,4S)-4-amino-5-[(1,1'-biphenyl)-4-yl]-2-methylpentanoate hydrochloride(149690-13-1)
• EPA Substance Registry System: ethyl (2S,4S)-4-amino-5-[(1,1'-biphenyl)-4-yl]-2-methylpentanoate hydrochloride(149690-13-1)

Safety Data

• Hazardous Substances Data: 149690-13-1(Hazardous Substances Data)

Downstream Products

• 149709-63-7 α-ethyl (αS,γS)-γ-<(3-carboxy-1-oxopropyl)amino>-α-methyl<1,1'-biphenyl>-4-pentanoate 
• 1038925-00-6 (3S,5S)-5-biphenyl-4-ylmethyl-3-methylpyrrolidin-2-one 
• 1038924-70-7 (3R,5S)-5-({[1,1'-biphenyl]-4-yl}methyl)-3-methylpyrrolidin-2-one 

Relevant articles and documents

NEW PROCESS AND INTERMEDIATES

The present invention relates to a new chemical synthesis, intermediates and catalysts useful for the preparation of the neprilysin (NEP) inhibitor sacubitril. It further relates to new intermediate compounds and their use for said new chemical synthesis route.