1497-83-2Relevant academic research and scientific papers
Structure of products of the reaction of 2-cyanoaziridine with carbonyl compounds
Koehler, K. F.,Zaddach, H.,Kadorkina, G. K.,Voznesenskii, V. N.,Chervin, I. I.,Kostyanovsky, R. G.
, p. 2049 - 2052 (1993)
The structure of azimexone (3), the product of the reaction of 2-cyanoaziridine with acetone, was confirmed on the basis of 1H and 13C NMR spectra.The formation of this product is accounted for by the α-aziridinoalkylating action of an intermediate containing a good leaving iminoyloxy group.Similar reactions were observed for 1-chloromethylaziridine and a 1-aziridinylmethylammonium salt (6), but not for 1-methoxymethylaziridine (7) and 1-aziridinemethanol. - Key words: 2-(2-cyanoaziridino)-2-(2-carbamoylaziridino)propane; 1-tert-butyl-2-carbamoylaziridine; α-1-aziridinoalkylation; 1H and 13C NMR spectra.
