1498-40-4 Usage
Description
ETHYLDICHLOROPHOSPHINE is a colorless to light yellow liquid with a pungent odor. It is denser than water and is classified as very toxic by inhalation.
Uses
Used in Chemical Synthesis:
ETHYLDICHLOROPHOSPHINE is used as a reagent for the production of various chemical compounds due to its reactive nature and ability to form phosphorus-carbon bonds.
Used in Pesticide Industry:
ETHYLDICHLOROPHOSPHINE is used as a precursor in the synthesis of certain pesticides, specifically organophosphate pesticides, which are effective in controlling pests in agriculture.
Used in Pharmaceutical Industry:
ETHYLDICHLOROPHOSPHINE is used as an intermediate in the production of some pharmaceuticals, particularly those containing phosphorus in their molecular structure.
Used in Flame Retardants:
ETHYLDICHLOROPHOSPHINE is used as a component in the formulation of flame retardants, which are essential in the manufacturing of materials with fire-resistant properties.
Synthesis Reference(s)
Canadian Journal of Chemistry, 41, p. 2299, 1963 DOI: 10.1139/v63-333The Journal of Organic Chemistry, 14, p. 429, 1949 DOI: 10.1021/jo01155a014
Air & Water Reactions
Highly flammable. Pyrophoric, will spontaneously ignite on contact with water or moisture in air. In water the compound also decomposes to form hydrochloric acid, [AAR 1991].
Reactivity Profile
ETHYL PHOSPHONOUS DICHLORIDE is an acid halide and organophosphate. Flammable/combustible material. May ignite on contact with air or moist air. May burn rapidly with flare-burning effect. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].
Health Hazard
Fire will produce irritating, corrosive and/or toxic gases. Inhalation of decomposition products may cause severe injury or death. Contact with substance may cause severe burns to skin and eyes. Runoff from fire control may cause pollution.
Fire Hazard
Flammable/combustible material. May ignite on contact with moist air or moisture. May burn rapidly with flare-burning effect. Some react vigorously or explosively on contact with water. Some may decompose explosively when heated or involved in a fire. May re-ignite after fire is extinguished. Runoff may create fire or explosion hazard. Containers may explode when heated.
Safety Profile
Moderately toxic by
inhalation. Corrosive. A severe irritant to
skin, eyes, and mucous membranes. When
heated to decomposition it emits very toxic
fumes of POx, Cl-, and phosphine. See also
PHOSPHINE.
Check Digit Verification of cas no
The CAS Registry Mumber 1498-40-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,9 and 8 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1498-40:
(6*1)+(5*4)+(4*9)+(3*8)+(2*4)+(1*0)=94
94 % 10 = 4
So 1498-40-4 is a valid CAS Registry Number.
InChI:InChI=1/C2H5Cl2P/c1-2-5(3)4/h2H2,1H3
1498-40-4Relevant articles and documents
Perry et al.
, p. 2299,2302 (1963)
van Linthoudt et al.
, p. 1307 (1979)
Microsynthesis and electron ionization mass spectral studies of O(S)-alkyl N,N-dimethyl alkylphosphono(thiolo)thionoamidates for Chemical Weapons Convention verification
Saeidian, Hamdollah,Babri, Mehran,Abdoli, Morteza,Sarabadani, Mansour,Ashrafi, Davood,Naseri, Mohammad Taghi
, p. 2805 - 2814 (2013/01/15)
RATIONALE The availability of mass spectra and interpretation skills are essential for unambiguous identification of the Chemical Weapons Convention (CWC)-related chemicals. The O(S)-alkyl N,N-dimethyl alkylphosphono(thiolo) thionoamidates are included in the list of scheduled CWC-related compounds, but there are very few spectra from these compounds in the literature. This paper examines these spectra and their mass spectral fragmentation routes. METHODS The title chemicals were prepared through microsynthetic protocols and were analyzed using electron ionization mass spectrometry with gas chromatography as a MS-inlet system. Structures of fragments were confirmed using analysis of fragment ions of deuterated analogs, tandem mass spectrometry and density functional theory (DFT) calculations. RESULTS Mass spectrometric studies revealed some interesting fragmentation pathways during the ionization process, such as alkene and amine elimination and McLafferty-type rearrangements. The most important fragmentation route of the chemicals is the thiono-thiolo rearrangement. DFT calculations are used to support MS results and to reveal relative preference formation of fragment ions. The retention indices (RIs) of all the studied compounds are also reported. CONCLUSIONS Mass spectra of the synthesized compounds were investigated with the aim to enrich the Organization for the Prohibition of Chemical Weapons (OPCW) Central Analytical Database (OCAD) which may be used for detection and identification of CWC-related chemicals during on-site inspection and/or off-site analysis such as OPCW proficiency tests. Copyright
Preparation and -Cycloaddition of Methylthio-chlorophosphanes RP(Cl)SMe (R = Me, Et, Ph)
Apitz, Joerg,Grobe, Joseph,Le Van, Duc
, p. 257 - 260 (2007/10/02)
The methylthio-chlorophosphanes RP(Cl)SMe are prepared in good yields (62-65percent) by condensation reactions of the corresponding dichlorophosphanes RPCl2 with methanethiol in the presence of trimethylamine (molar ratio 1:1:1). 1 and 3 have been used to produce 3-phospholene sulfides in a one-pot process by reaction with 1,3-dienes at 70 to 100 deg C.Reaction proceeds via -cycloadducts, which in suitable cases can be isolated and used for the preparation of the corresponding 3-phospholene oxides.New compounds were characterized by elemental analysis and spectroscopic investigations (NMR, MS). - Keywords: Methylthio-chlorophosphanes, 3-Phospholene Sulfides and Oxides, Mass Spectra, NMR Spectra
