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Usage

Uses

Used in Organic Synthesis:
4-(4-bromophenyl)-2,6-diphenylpyridine is used as a building block for the synthesis of various organic compounds due to its unique structure and reactivity. Its presence in the molecular framework can impart specific properties to the synthesized compounds, making it a versatile component in organic chemistry.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 4-(4-bromophenyl)-2,6-diphenylpyridine is used as a key intermediate in the development of pharmaceutical compounds. Its unique structure can be exploited to design and synthesize novel drug candidates with potential therapeutic applications.
Used in Material Science:
4-(4-bromophenyl)-2,6-diphenylpyridine is utilized in material science for the development of advanced materials with specific properties. Its incorporation into the molecular structure of materials can enhance their performance in various applications, such as optoelectronics, sensors, and other high-tech industries.
Used in Research and Industrial Applications:
Due to its interesting properties, such as fluorescence and photophysical behavior, 4-(4-bromophenyl)-2,6-diphenylpyridine is a valuable compound in various research and industrial applications. It can be used to study the fundamental aspects of its photophysical properties and to develop new applications based on its unique characteristics.

InChI:InChI=1/C23H16BrN/c24-21-13-11-17(12-14-21)20-15-22(18-7-3-1-4-8-18)25-23(16-20)19-9-5-2-6-10-19/h1-16H

Upstream product

• 22966-09-2 (2E)-3-(4-bromophenyl)-1-phenylprop-2-en-1-one 
• 16883-69-5 N-phenacylpyridinium bromide 
• 98-85-1 1-Phenylethanol 
• 873-75-6 4-bromobenzenemethanol 
• 98-86-2 acetophenone 
• 1774-66-9 3-(4-bromophenyl)-1-phenylprop-2-en-1-one 
• 497103-41-0 3-(4-bromophenyl)-1,5-diphenylpentane-1,5-dione 
• 106-38-7 para-bromotoluene 
• 586-76-5 4-Bromobenzoic acid 
• 1122-91-4 4-bromo-benzaldehyde 
• 75-05-8 acetonitrile 
• 98-80-6 phenylboronic acid 
• 3959-07-7 4-Bromobenzylamine 
• 536-74-3 phenylacetylene 

Downstream Products

• 97419-28-8 4-(2,6-diphenylpyridin-4-yl)benzaldehyde 
• 1192455-03-0 2,6-diphenyl-4-(4-vinylphenyl)pyridine 
• 1360464-84-1 4-(4-ethynylphenyl)-2,6-diphenylpyridine 
• 1360464-85-2 4-[4-(2,6-diphenylpyridin-4-yl)phenyl]-2-methylbut-3-yn-2-ol 
• 31380-31-1 4-(4-biphenylyl)-2,6-diphenylpyridine 

Relevant academic research and scientific papers

Exploring the C^N^C theme: Synthesis and biological properties of tridentate cyclometalated gold(III) complexes

A family of cyclometalated Au(III) complexes featuring a tridentate C^N^C scaffold has been synthesized and characterized. Microwave assisted synthesis of the ligands has also been exploited and optimized. The biological properties of the thus formed comp

Synthesis of a functionalized polymer based on a calix[4]resorcinarene via covalently anchored cationic moieties: A reactive solid support for ring transformation and expansion of thiopyrylium salts

In this work, for the first time, a cationic polymer containing pendant pyridinium groups was synthesized via post-functionalization of the polymeric backbone based on a calix[4]resorcinarene, and characterized by AFM, TEM, analytical CHN, TGA, and DTG te

Silver(I) Complexes of Diphenylpyridines: Crystal Structures, Luminescence Studies, Theoretical Insights, and Biological Activities

A series of simple two-coordinated cationic silver(I) complexes, namely, [Ag{4-(4-R1-phenyl)-2,6-diphenylpyridine}2]X (X=ClO4 ?, BF4 ?, or SO3CF3 ?), with different electron-donating or -withdrawing groups (e.g., R1=N(Me)2, Me, H, Cl, and Br) on the phenyl ring, were successfully prepared. Extensive characterization of these complexes by various NMR spectroscopy techniques and mass spectrometry was further corroborated by single-crystal XRD analyses. Detailed photophysical investigations of [Ag{4-(4-N,N-dimethylaminophenyl)-2,6-diphenylpyridine}2]ClO4 (C1) displayed a strong room-temperature fluorescence in solution with an anomalously high luminescence quantum yield of 0.83. The effects of distinct substituent groups (C2–C5), π-conjugated aromatic rings (C6 and C7), and anions (C8 and C9) on the photoluminescence properties were evaluated. Furthermore, DFT and time-dependent DFT calculations were performed to discern the composition of the excited state, as well as to confirm the obtained relative emission energies upon substitution with electronically different ligands. These results indicated that the strong electron-donating substituent of N,N-dimethylamine played an important role in the unprecedented high luminescence quantum yield of C1. In addition, preliminary antimicrobial studies and confocal microscopy fluorescent imaging of HeLa cells labeled with these complexes reveal their potential applications in biological activities.

An efficient synthesis of 2,4,6-triarylpyridines via solvent-free reaction between acetophenoneoximes and aldehydes

An efficient synthesis of 2,4,6-triarylpyridines is described. Heating a mixture of an acetophenoneoxime and an aldehyde under solvent-free conditions afforded Kr?hnke pyridines in excellent yields. In this method acetophenoneoximes are directly used for the preparation of Kr?hnke pyridines under metal-free conditions. Georg Thieme Verlag Stuttgart New York.

TMSOTf-mediated Kr?hnke pyridine synthesis using HMDS as the nitrogen source under microwave irradiation

An efficient protocol for the preparation of pyridine skeletons has been successfully developed involving the TMSOTf/HMDS (trifluoromethanesulfonic acid/hexamethyldisilane) system for the intermolecular cyclization of chalcones under MW (microwave) irradiation conditions. This method provides a facile approach to synthesize 2,4,6-triaryl or 3-benzyl-2,4,6-triarylpyridines in good to excellent yields. Interestingly, the 2,6-diazabicyclo[2.2.2]oct-2-ene core was obtained by changing the acid additive to Sn(OTf)2, and the desired product was also confirmed using X-ray single-crystal diffraction analysis.

Application of salicylic acid as an eco-friendly and efficient catalyst for the synthesis of 2,4,6-triaryl pyridine, 2-amino-3-cyanopyridine, and polyhydroquinoline derivatives

In this study, three eco-friendly, efficient, and convenient protocols have been reported for one-pot synthesis of 2,4,6-triaryl pyridine, 2-amino-3-cyanopyridine, and polyhydroquinoline derivatives using salicylic acid as a catalyst under solvent-free condition. The reported protocols offer several significant advantages such as the application of a nontoxic, neutral, and cheap catalyst, environmentally friendly conditions, the easy isolation of products by filtering, short reaction times, simple methodology, and good yields.

D-π-A type tetraphenyl ethynylphenyl substituted pyridine conjugated luminous small molecule and synthesis method thereof

The invention discloses D-π-A type tetraphenylethynylphenyl substituted pyridine conjugated luminous small molecule and a synthesis method thereof. 4 - Bromobenzaldehyde. The aryl acetophenone and ammonium acetate undergo Chichibabin reaction under the ca

Synthesis of Kr?hnke pyridines through iron-catalyzed oxidative condensation/double alkynylation/amination cascade strategy

An efficient protocol for the synthesis of symmetrical and unsymmetrical 2,4,6-trisubstituted pyridines via oxidative cascade annulation of arylacetylenes with benzylamines has been developed. The reaction proceeds smoothly utilizing iron(II) triflate as a catalyst and molecular oxygen as an oxidant with broad substrate scope. Mechanistic studies reveal that the reaction may be experiences an oxidative condensation followed by double alkynylation and amination process.

Compound, electron transport material and organic electroluminescent device

The present application provides a compound of general formula (I), which can be used in an electron transport material. The compound is high in bond energy among atoms, good in thermal stability, beneficial to solid-state accumulation among molecules, hi

Pyridine Skeleton Synthesis Using Acetonitrile as C4N1 Units and Solvent

The first [3 + 2 + 1] methodology for pyridine skeleton synthesis via cascade carbopalladation/cyclization of acetonitrile, arylboronic acids, and aldehydes was developed. This reaction proceeds via six step tandem reaction sequences involving the carbopalladation reaction of acetonitrile, a nucleophilic addition, a condensation, an intramolecular Michael addition, cyclization, and aromatization. Delightfully, both palladium acetate and supported palladium nanoparticles catalyzed this reaction with similar catalytic performance. The characterization results of the fresh and used supported palladium nanoparticle catalysts indicated that the reaction might be performed via a Pd(0)/Pd(II) catalytic cycle that began with Pd(0). Furthermore, the products showed good fluorescence characteristics. The green homogeneous/heterogenous catalytic methodologies pave a new way for constructing the pyridine skeleton.