149836-44-2

Upstream product

• 7536-59-6 Boc-Glu(OBzl)-ONp 
• 100-44-7 benzyl chloride 
• 2188-18-3 Boc-Arg(NO₂)-OH 
• 94770-45-3 benzyl Nα-Boc-Nω-nitro-L-argininate 
• 13574-13-5 Boc-Glu(OBzl)-OH 
• 7672-27-7 N'-nitro-L-arginine benzyl ester 

Downstream Products

• 1235563-75-3 benzyl Nα-Boc-Nω-nitro-L-arginyl-(γ-benzyl α-L-glutamyl)-Nω-nitro-L-argininate 
• 1235563-81-1 benzyl N-[1-(diethoxyphosphoryl)-2,3-dihydro-1H-inden-1-yl]-(γ-benzyl)-α-L-glutamyl-Nω-nitro-L-argininate 
• 1235563-84-4 benzyl [Nα-(1-(diethoxyphosphoryl)-2,3-dihydro-1H-inden-1-yl)-Nω-nitro-L-arginyl]-(γ-benzyl)-α-L-glutamyl-Nω-nitro-L-argininate 
• 1235563-87-7 benzyl [Nα-(5-benzyloxycarbonyl-1-(diethoxyphosphoryl)-2,3-dihydro-1H-inden-1-yl)-Nω-nitro-L-arginyl]-(γ-benzyl)-α-L-glutamyl-Nω-nitro-L-argininate 
• 1235563-92-4 benzyl (γ-benzyl α-L-glutamyl)-Nω-nitro-L-argininate trifluoroacetate 
• 149836-47-5 Z(OMe)-Arg(NO₂)-Val-Val-Glu(OBzl)-Arg(NO₂)-OBzl 
• 149836-46-4 Boc-Val-Val-Glu(OBzl)-Arg(NO₂)-OBzl 
• 149836-45-3 Boc-Val-Glu(OBzl)-Arg(NO₂)-OBzl 
• 149836-39-5 Z-Gly-Pro-Arg(NO₂)-Val-Val-Glu(OBzl)-Arg(NO₂)-OBzl 

Relevant academic research and scientific papers

Synthesis of a "memory tripeptide" (Arg-Glu-Arg, RER) and the Kabachnik-Fields reaction with di-and tripeptides as a method for the synthesis of phosphorus-containing peptide analogs

Methods for the synthesis of potential "twin-drugs" containing fragments of the glutamate receptor antagonist and cognitive function enhancing oligopeptides were developed. The "memory tripeptide" Arg-Glu-Arg (RER) containing the tripeptide sequence of a protein APP328-330, a β-amyloid precursor, was synthesized. A method for the synthesis of α-aminophosphonates with oligopeptides as the amine component of the one-pot three-component Kabachnik-Fields reaction was developed. A method for the synthesis of phosphonopeptides by the introduction of α- aminophosphonates into the peptide chain was proposed.

Amino acids and peptides. XVII. Synthesis of peptides related to N-terminal portion of fibrin alpha-chain and their inhibitory effect on fibrinogen/thrombin clotting.

Various peptides related to N-terminal portion of fibrin alpha-chain were synthesized by the solution method and the solid-phase method, and their inhibitory effect on fibrinogen/thrombin clotting was examined. Extension of peptide chain from N-terminal t