1235563-87-7

Upstream product

• 1235563-75-3 benzyl Nα-Boc-Nω-nitro-L-arginyl-(γ-benzyl α-L-glutamyl)-Nω-nitro-L-argininate 
• 762-04-9 Diethyl phosphonate 
• 1235563-93-5 benzyl 1-oxo-2,3-dihydro-1H-indene-5-carboxylate 
• 94770-45-3 benzyl Nα-Boc-Nω-nitro-L-argininate 
• 149836-44-2 benzyl Nα-Boc-(γ-benzyl α-L-glutamyl)-Nω-nitro-L-argininate 
• 1235563-92-4 benzyl (γ-benzyl α-L-glutamyl)-Nω-nitro-L-argininate trifluoroacetate 
• 2188-18-3 Boc-Arg(NO₂)-OH 
• 100-44-7 benzyl chloride 

Relevant academic research and scientific papers

Synthesis of a "memory tripeptide" (Arg-Glu-Arg, RER) and the Kabachnik-Fields reaction with di-and tripeptides as a method for the synthesis of phosphorus-containing peptide analogs

Methods for the synthesis of potential "twin-drugs" containing fragments of the glutamate receptor antagonist and cognitive function enhancing oligopeptides were developed. The "memory tripeptide" Arg-Glu-Arg (RER) containing the tripeptide sequence of a protein APP328-330, a β-amyloid precursor, was synthesized. A method for the synthesis of α-aminophosphonates with oligopeptides as the amine component of the one-pot three-component Kabachnik-Fields reaction was developed. A method for the synthesis of phosphonopeptides by the introduction of α- aminophosphonates into the peptide chain was proposed.