1235563-92-4

Basic information

• Product Name: benzyl (γ-benzyl α-L-glutamyl)-Nω-nitro-L-argininate trifluoroacetate
• Synonyms: benzyl (γ-benzyl α-L-glutamyl)-Nω-nitro-L-argininate trifluoroacetate
• CAS NO: 1235563-92-4
• Molecular Weight: 642.589
• Mol File: 1235563-92-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: benzyl (γ-benzyl α-L-glutamyl)-Nω-nitro-L-argininate trifluoroacetate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (γ-benzyl α-L-glutamyl)-Nω-nitro-L-argininate trifluoroacetate(1235563-92-4)
• EPA Substance Registry System: benzyl (γ-benzyl α-L-glutamyl)-Nω-nitro-L-argininate trifluoroacetate(1235563-92-4)

Safety Data

• Hazardous Substances Data: 1235563-92-4(Hazardous Substances Data)

Upstream product

• 100-44-7 benzyl chloride 
• 2188-18-3 Boc-Arg(NO₂)-OH 
• 149836-44-2 benzyl Nα-Boc-(γ-benzyl α-L-glutamyl)-Nω-nitro-L-argininate 
• 76-05-1 trifluoroacetic acid 
• 94770-45-3 benzyl Nα-Boc-Nω-nitro-L-argininate 

Downstream Products

• 1235563-84-4 benzyl [Nα-(1-(diethoxyphosphoryl)-2,3-dihydro-1H-inden-1-yl)-Nω-nitro-L-arginyl]-(γ-benzyl)-α-L-glutamyl-Nω-nitro-L-argininate 
• 1235563-87-7 benzyl [Nα-(5-benzyloxycarbonyl-1-(diethoxyphosphoryl)-2,3-dihydro-1H-inden-1-yl)-Nω-nitro-L-arginyl]-(γ-benzyl)-α-L-glutamyl-Nω-nitro-L-argininate 
• 1235563-81-1 benzyl N-[1-(diethoxyphosphoryl)-2,3-dihydro-1H-inden-1-yl]-(γ-benzyl)-α-L-glutamyl-Nω-nitro-L-argininate 
• 1235563-75-3 benzyl Nα-Boc-Nω-nitro-L-arginyl-(γ-benzyl α-L-glutamyl)-Nω-nitro-L-argininate 

Relevant articles and documents

Synthesis of a "memory tripeptide" (Arg-Glu-Arg, RER) and the Kabachnik-Fields reaction with di-and tripeptides as a method for the synthesis of phosphorus-containing peptide analogs

Methods for the synthesis of potential "twin-drugs" containing fragments of the glutamate receptor antagonist and cognitive function enhancing oligopeptides were developed. The "memory tripeptide" Arg-Glu-Arg (RER) containing the tripeptide sequence of a protein APP328-330, a β-amyloid precursor, was synthesized. A method for the synthesis of α-aminophosphonates with oligopeptides as the amine component of the one-pot three-component Kabachnik-Fields reaction was developed. A method for the synthesis of phosphonopeptides by the introduction of α- aminophosphonates into the peptide chain was proposed.