149873-57-4Relevant articles and documents
Synthesis of 4-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-6-(substituted phenyl)pyrimidin-2-ol analogues as anti-inflammatory and analgesic agents
Alam, Muhammad Jahangir,Ahsan, Mohamed Jawed,Alam, Ozair,Khan, Suroor Ahmad
, p. 776 - 782 (2013/12/04)
A series of 16 novel 4-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-6- (substituted-phenyl)pyrimidin-2-ol analogues was synthesized in satisfactory yields after toxicity prediction and drug score studies by Osiris software followed by anti-inflammatory, a
Synthesis and pharmacological study of 1-acetyl/propyl-3-aryl-5-(5-chloro- 3-methyl-1-phenyl-1H-pyrazol-4-yl)-2-pyrazoline
Girisha,Kalluraya, Balakrishna,Narayana, Vijaya,Padmashree
experimental part, p. 4640 - 4644 (2010/10/19)
A series of 1-acetyl/propyl-3-aryl-5-(5-chloro-3-methyl-1-phenyl-1H- pyrazol-4-yl)-2-pyrazolines were synthesized in one step by condensing suitably substituted propenones, hydrazine and acetic/propionic acid. The newly synthesized pyrazolines were characterized by analytical and spectral data. The new compounds were screened for analgesic and anti-inflammatory activity and most of them showed good activity comparable with that of standard drugs Pentazocin and Diclofinac sodium respectively.
Design, synthesis, and characterization of some novel pyrazolo [1,5-a] pyrimidines as potent antimicrobial agents
Dawane, Bhaskar S.,Konda, Shankaraiah G.,Zangade, Sainath B.
experimental part, p. 1250 - 1254 (2010/11/18)
(Chemical Equation Presented) A novel series of pyrazolo [1,5-a] pyrimidines were synthesized by the condensation of substituted chalcones with 5-amino pyrazole in presence of dimethyl formamide. All the synthesized products were characterized by the spec