149883-42-1

Upstream product

• 67-56-1 methanol 
• 562858-39-3 (5S,8S,9R)-8-benzoyl-2-((2S,4S,5S)-(Z)-5-(but-1-enyl)-2-methyl-[1,3]dioxolan-4-yl)-8,9-dihydroxy-3-methyl-1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione 
• 660842-21-7 (5S,9S)-2-((Z)-(1S,2S)-1,2-Bis-methoxymethoxy-hex-3-enyl)-9-methoxymethoxy-3-methyl-8-[1-phenyl-meth-(Z)-ylidene]-1-oxa-7-aza-spiro[4.4]non-2-ene-4,6-dione 
• 660842-20-6 (5S,8R,9R)-8-benzyl-2-[(1S,2S,3Z)-1,2-bis(methoxymethoxy)-3-hexenyl]-8-hydroxy-9-methoxymethoxy-3-methyl-1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione 
• 660842-19-3 (S)-5-((Z)-(1S,2S)-1,2-Bis-methoxymethoxy-hex-3-enyl)-2-((R)-1-methoxymethoxy-2-oxo-3-phenyl-propyl)-4-methyl-3-oxo-2,3-dihydro-furan-2-carboxylic acid amide 
• 660842-18-2 (5S,8R,9S)-8-benzyl-2-[(1S,2S,3Z)-1,2-bis(methoxymethoxy)-3-hexenyl]-9-methoxymethoxy-3-methyl-1,7-dioxaspiro[4.4]non-2-ene-4,6-dione 
• 499121-02-7 (3S,4S,5R)-5-Benzyl-3-((Z)-(4R,5S)-3-hydroxy-4,5-bis-methoxymethoxy-2-methyl-non-6-enoyl)-3,4-bis-triethylsilanyloxy-dihydro-furan-2-one 
• 499121-03-8 (3S,4S,5R)-5-Benzyl-3-hydroxy-3-((Z)-(4R,5S)-3-hydroxy-4,5-bis-methoxymethoxy-2-methyl-non-6-enoyl)-4-triethylsilanyloxy-dihydro-furan-2-one 
• 499121-04-9 (5S,8R,9S)-8-benzyl-2-[(1S,2S,3Z)-1,2-bis(methoxymethoxy)-3-hexenyl]-2-hydroxy-3-methyl-9-triethylsiloxy-1,7-dioxaspiro[4.4]nonane-4,6-dione 
• 499120-89-7 (5S,8R,9S)-8-benzyl-2-[(1S,2S,3Z)-1,2-bis(methoxymethoxy)-3-hexenyl]-3-methyl-9-triethylsiloxy-1,7-dioxaspiro[4.4]non-2-ene-4,6-dione 
• 499121-08-3 (2R,3S,4R)-4-benzyl-2-[(1R)-1-(benzyloxy)propyl]-2,3-bis(triethylsiloxy)-4-butanolide 
• 499121-09-4 (2R,3S,4R)-4-benzyl-2-[(1R)-1-hydroxypropyl]-2,3-bis(triethylsiloxy)-4-butanolide 
• 499120-90-0 (2S,3S,4R)-4-benzyl-2-propanoyl-2,3-bis(triethylsiloxy)-4-butanolide 
• 1054611-03-8 (4R,5S)-4-((R)-1-Benzyloxy-propyl)-2,2-dimethyl-5-trityloxymethyl-4-vinyl-[1,3]dioxolane 

Downstream Products

• 58523-30-1 pseurotin A 

Relevant academic research and scientific papers

Total syntheses of natural pseurotins A and F2 and azaspirene

Total syntheses of natural pseurotins A (1) and F2 (8-O-demethylpseurotin A) (2) and structurally related azaspirene (3), each possessing a novel heterospirocyclic system, i.e., 1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione skeleton, have been accom

Total syntheses of natural pseurotins A, F2, and azaspirene

We describe the total syntheses of natural pseurotins A and F2, inhibitors of chitin synthase, both of which possess an unusual 1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione ring system. The total syntheses of these spiro-hetereocyclic natural produ

Asymmetric total synthesis of pseurotin A

(Matrix presented) The asymmetric total syntheses of pseurotin A and 8-O-demethylpseurotin A have been accomplished. Key reactions are a NaH-promoted intramolecular cyclization of an alkynylamide to form a γ-lactam, an aldol reaction of a benzylidene-subs