150194-06-2

Upstream product

• 150194-05-1 Ethyl 1-benzenesulfonyl-3-methyl-2-indolecarboxylate 
• 26304-51-8 ethyl 3-methyl-indole-2-carboxylate 
• 98-09-9 benzenesulfonyl chloride 

Downstream Products

• 1150111-75-3 ethyl 1-phenylsulfonyl-3-(3,4-dimethoxybenzyl)-1H-indole-2-carboxylate 
• 1372674-70-8 ethyl 3-(3-bromo-3-phenylallyl)-1-(phenylsulfonyl)-1H-indole-2-carboxylate 
• 1372674-73-1 ethyl 3-(3-bromo-3-phenylallyl)-1-(phenylsulfonyl)-1H-indole-2-carboxylate 
• 856111-18-7 ethyl 1-phenylsulfonyl-3-phenylthiomethylindole-2-carboxylate 

Relevant academic research and scientific papers

A Novel Dimerization of Ethyl 3-Cyanomethyl-2-indolecarboxylate

Reaction of ethyl 1-benzenesulfonyl-3-bromomethyl-2-indolecarboxylate (3) with KCN in THF resulted in the formation of ethyl 1-benzenesulfonyl-3-cyanomethyl-2-indolecarboxylate (4) and two other dimeric indole derivatives 5 and 6.The mechanism of formatio

Unusual dimerization of N-protected bromomethylindoles/benzyl bromide with arylmetal halides: generation of indolylmethyl/benzyl radical

A detailed study on the interaction of N-protected bromomethylindoles with various types of aryl/alkyl Grignard is reported. Full experimental details on the mechanism of the unusual dimerization reaction are presented.

Synthesis of N-protected indolaldehydes using modified Hass procedure

A detailed study on oxidation of N-protected bromomethylindoles into the respective aldehydes was carried out. Using a modified Hass procedure, synthesis of aryl-/hetero-aryl aldehydes in particular indolaldehydes is achieved in reasonable yields.

An efficient preparation of 1-phenylsulfonylindolyl methyl sulfoxides using KF/m-CPBA

A variety of 1-phenylsulfonylindolylmethyl sulfides are selectively oxidized to the corresponding sulfoxides using a hitherto unexplored KF/m-CPBA system. A major advantage is the absence of over-oxidation.