150206-15-8 Usage
Description
5(6)-CARBOXYFLUORESCEIN-NHS DIACETATE, also known as 6-Carboxyfluorescein 3’,6’-Diacetate N-Succinimidyl Ester, is a derivative of 6-Carboxyfluorescein (C178225). It is a light yellow powder that is used for various applications in the field of cell biology and immunology. 5(6)-CARBOXYFLUORESCEIN-NHS DIACETATE is known for its ability to covalently label long-lived intracellular molecules with a fluorescent dye, which aids in the visualization and tracking of these molecules within cells.
Uses
Used in Cell Biology:
5(6)-CARBOXYFLUORESCEIN-NHS DIACETATE is used as a fluorescent labeling agent for monitoring long-lived intracellular molecules. The application reason is its ability to covalently bind to these molecules, allowing for their visualization and tracking within cells.
Used in Immunology:
In the field of immunology, 5(6)-CARBOXYFLUORESCEIN-NHS DIACETATE is used as a proliferation marker for lymphocytes. The application reason is its ability to label long-lived intracellular molecules, which helps in tracking the proliferation of these immune cells.
Used in Pharmaceutical Research:
5(6)-CARBOXYFLUORESCEIN-NHS DIACETATE is used as a research tool in the development of new drugs and therapies. The application reason is its utility in studying cellular processes and immune responses, which can provide valuable insights for drug discovery and development.
Used in Diagnostics:
In the diagnostics industry, 5(6)-CARBOXYFLUORESCEIN-NHS DIACETATE is used as a component in the development of diagnostic assays and tests. The application reason is its ability to label and visualize specific cellular targets, which can aid in the detection and monitoring of various diseases and conditions.
Used in Biotechnology:
In the biotechnology industry, 5(6)-CARBOXYFLUORESCEIN-NHS DIACETATE is used as a tool for protein labeling and tracking. The application reason is its ability to covalently bind to proteins, allowing for the study of protein dynamics, interactions, and localization within cells.
Check Digit Verification of cas no
The CAS Registry Mumber 150206-15-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,0,2,0 and 6 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 150206-15:
(8*1)+(7*5)+(6*0)+(5*2)+(4*0)+(3*6)+(2*1)+(1*5)=78
78 % 10 = 8
So 150206-15-8 is a valid CAS Registry Number.
150206-15-8Relevant articles and documents
Separating the isomers - Efficient synthesis of the N-hydroxysuccinimide esters of 5 and 6-carboxyfluorescein diacetate and 5 and 6-carboxyrhodamine B
Brunet, Aurlie,Aslam, Tashfeen,Bradley, Mark
, p. 3186 - 3188 (2015/02/05)
Diacetate protection of 5 and 6-carboxyfluorescein followed by synthesis of the N-hydroxysuccinimide esters allowed ready separation of the two isomers on a multi-gram scale. The 5 and 6-carboxyrhodamine B N-hydroxysuccinimide esters were also readily synthesised and separated.