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1503-54-4

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1503-54-4 Usage

General Description

O-acetyl-5-iodosalicylic acid is a chemical compound with the molecular formula C9H7IO4. It is an iodinated derivative of salicylic acid and contains an acetyl group attached to the hydroxyl group at the ortho position of the phenolic ring. O-acetyl-5-iodosalicylic acid has potential applications in the field of organic synthesis and medicinal chemistry. It is commonly used as a reagent in the synthesis of pharmaceutical compounds and other organic molecules. In addition, O-acetyl-5-iodosalicylic acid has shown antimicrobial and antioxidant properties, making it a potential candidate for the development of new drugs and pharmaceuticals. Overall, this compound has diverse potential applications in various fields of science and industry.

Check Digit Verification of cas no

The CAS Registry Mumber 1503-54-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,0 and 3 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1503-54:
(6*1)+(5*5)+(4*0)+(3*3)+(2*5)+(1*4)=54
54 % 10 = 4
So 1503-54-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H7IO4/c1-5(11)14-8-3-2-6(10)4-7(8)9(12)13/h2-4H,1H3,(H,12,13)

1503-54-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-acetyloxy-5-iodobenzoic acid

1.2 Other means of identification

Product number -
Other names 5-Iodoacetylsalicylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1503-54-4 SDS

1503-54-4Relevant articles and documents

A highly practical route to 2-methylchromones from 2-acetoxybenzoic acids

Jung,Min,Park

, p. 1837 - 1845 (2007/10/03)

2-Methylchromones were accessed via a keto ester condensation on 2-acetoxybenzoyl chloride, followed by cyclization and decarboxylation. No column chromatography was required in the process.

Synthesis and biological activity of novel 1,3-benzoxazine derivatives as K+ channel openers

Yamamoto, Satoshi,Hashiguchi, Shohei,Miki, Shokyo,Igata, Yumiko,Watanabe, Toshifumi,Shiraishi, Mitsuru

, p. 734 - 745 (2007/10/03)

A new series of 1,3-benzoxazine derivatives with a 2-pyridine 1-oxide group at C4 was designed to explore novel K+ channel openers. Synthesis was carried out by using a palladium(0)-catalyzed carbon-carbon bond formation reaction of imino-triflates with organozinc reagents and via a new one-pot 1,3-benzoxazine skeleton formation reaction of benzoylpyridines. The compounds were tested for vasorelaxant activity in tetraethylammonium chloride (TEA) and BaCl2-induced and high KCl-induced contraction of rat aorta to identify potential K+ channel openers, and also for oral hypotensive effects in spontaneously hypertensive rats. An electron- withdrawing group with the proper shape at C6 and a methyl or halogens group at C7 of the 1,3-benzoxazine nucleus were required for the development of optimal vasorelaxant and hypotensive activity. In particular, 2-(6-bromo-7- chloro-2,2-dimethyl-2H-1,3-benzoxazin-4-yl)pyridine 1-oxide (71) showed more potent vasorelaxant activity (EC50=0.14 μM) against TEA and BaCL2- induced contraction and longer-lasting hypotensive effects than cromakalim (1).

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