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119-30-2

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119-30-2 Usage

Chemical Properties

white to slightly beige powder

Uses

2-hydroxy-5-iodobenzoic acid is a reagent in various organic chemical reactions leading to pharmaceutical compounds. It is involved in the synthesis of labeled benzamide analogs for tumor imaging as well as the synthesis of the dye, Congo Red, for biological analyses.

Purification Methods

Crystallise the acid from water. [Beilstein 10 H 112.]

Check Digit Verification of cas no

The CAS Registry Mumber 119-30-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,1 and 9 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 119-30:
(5*1)+(4*1)+(3*9)+(2*3)+(1*0)=42
42 % 10 = 2
So 119-30-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H5IO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,(H,10,11)/p-1

119-30-2 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (B21291)  5-Iodosalicylic acid, 97%   

  • 119-30-2

  • 25g

  • 383.0CNY

  • Detail
  • Alfa Aesar

  • (B21291)  5-Iodosalicylic acid, 97%   

  • 119-30-2

  • 100g

  • 716.0CNY

  • Detail
  • Alfa Aesar

  • (B21291)  5-Iodosalicylic acid, 97%   

  • 119-30-2

  • 500g

  • 2860.0CNY

  • Detail

119-30-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Iodosalicylic acid

1.2 Other means of identification

Product number -
Other names 2-hydroxy-5-iodobenzoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:119-30-2 SDS

119-30-2Related news

The determination of the sodium salt of 5-Iodosalicylic acid (cas 119-30-2) and its metabolites in urine08/30/2019

A method for the determination of the sodium salt of 5-iodosalicyhc acid (5-I-S-Na) and total iodine is described. The method for the determination of 5-T-S-Na is based on the ultraviolet light absorption of this substance. Control experiments with the method for the determination of 5-1-S-Na an...detailed

The absorption of iodine from 5-Iodosalicylic acid (cas 119-30-2) by hydroponically grown lettuce08/28/2019

The aim of the study was to determine the effect of various doses of 5-iodosalicylic acid (5I-SA; organoiodine compound) on the growth, chemical composition, and efficiency of iodine biofortification of lettuce cultivated in a nutrient film technique hydroponic system. The additional purpose was...detailed

119-30-2Relevant articles and documents

Iodination of aromatic compounds with iodine and n-butyltriphenylphosphonium peroxodisulfate

Tajik,Esmaeili,Mohammadpoor-Baltork,Ershadi,Tajmehri

, p. 1319 - 1323 (2003)

Iodine and n-butyltriphenylphosphonium peroxodisulfate can be successfully used for the iodination of some aromatic compounds in acetonitrile as solvent. The yields obtained are good to excellent.

Novel, water-based procedure for the mono iodination of aromatic amines and phenols

Sathiyapriya,Joel Karunakaran

, p. 1915 - 1917 (2006)

A mixture of potassium chlorate and potassium iodide was found to be a good iodinating agent for various aromatic amines and phenols with excellent yields in the presence of mineral acid in aqueous medium. Copyright Taylor & Francis Group, LLC.

Sulfated polyborate-H2O assisted tunable activation of N-iodosuccinimide for expeditious mono and diiodination of arenes

Misal, Balu,Palav, Amey,Ganwir, Prerna,Chaturbhuj, Ganesh

supporting information, (2021/05/26)

Owing to both Lewis and Bronsted acid active sites on sulfated polyborate under homogenous conditions, we were keen on developing iodination protocol of arenes that can meet the requirement of regioselectivity and higher yield. The sulfated polyborate activates N-iodosuccinimide for mono iodination of highly activated substrates viz. phenols, anilines under anhydrous condition. Water tunes sulfated polyborate to generate more Bronsted acid sites resulting in rapid activation of NIS for diiodination. The protocol was equally applicable to diiodination of 4-hydroxyphenylacetic acid to synthesize 4-hydroxy-3,5-diiodophenylacetic acid, an intermediate of tiratricol, a thyroid treatment drug. This protocol was further integrated via one-pot sequential iodination and Sonogashira coupling to synthesize aryl acetylenes, building blocks for the synthesis of a variety of specialty chemicals, API, and natural products.

HPK1 INHIBITORS, PREPARATION METHOD AND APPLICATION THEREOF

-

Page/Page column 158, (2019/11/12)

Disclosed are HPK-1 inhibitors having a structure represented by Formula (X), pharmaceutical compositions comprising the HPK-1 inhibitors, methods of using the HPK-1 inhibitors, such as treating cancers, methods of preparing the HPK-1 inhibitors, and the synthetic intermediates.

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