150349-10-3

Basic information

• Product Name: 2-<(1R,3S,4S)-1-benzyl-4<(tert-butoxycarbonyl)amino>-3-(tert-butyldimethylsiloxy)-5-phenylpentyl>-5-(2-methylpropionyl)imidazole
• Synonyms: 2-<(1R,3S,4S)-1-benzyl-4<(tert-butoxycarbonyl)amino>-3-(tert-butyldimethylsiloxy)-5-phenylpentyl>-5-(2-methylpropionyl)imidazole
• CAS NO: 150349-10-3
• Molecular Weight: 619.92
• Mol File: 150349-10-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-<(1R,3S,4S)-1-benzyl-4<(tert-butoxycarbonyl)amino>-3-(tert-butyldimethylsiloxy)-5-phenylpentyl>-5-(2-methylpropionyl)imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-<(1R,3S,4S)-1-benzyl-4<(tert-butoxycarbonyl)amino>-3-(tert-butyldimethylsiloxy)-5-phenylpentyl>-5-(2-methylpropionyl)imidazole(150349-10-3)
• EPA Substance Registry System: 2-<(1R,3S,4S)-1-benzyl-4<(tert-butoxycarbonyl)amino>-3-(tert-butyldimethylsiloxy)-5-phenylpentyl>-5-(2-methylpropionyl)imidazole(150349-10-3)

Safety Data

• Hazardous Substances Data: 150349-10-3(Hazardous Substances Data)

Upstream product

• 149976-34-1 (2R,4S,5S)-2-benzyl-5-<(tert-butoxycarbonyl)amino>-4-(tert-butyldimethylsiloxy)-N-(isoxazol-4-yl)-6-phenylhexanamide 
• 159949-20-9 2-<(2R,3S,4S)-1-benzyl-4-<(tert-butoxycarbonyl)amino>-3-(tert-butyldimethylsiloxy)-5-phenylpentyl>-5-formylimidazole 
• 98818-51-0 N-(1,1-dimethylethoxycarbonyl)-5(S)-amino-4(S)-(t-butyldimethylsilyloxy)-6-phenyl-2(R)-(phenylmethyl)hexanoic acid 
• 541552-04-9 2-<(1R,3S,4S)-1-benzyl-4<(tert-butoxycarbonyl)amino>-3-(tert-butyldimethylsiloxy)-5-phenylpentyl>-5-(1-hydroxy-2-methylpropyl)imidazole 

Downstream Products

• 150348-85-9 [(1S,2S,4R)-1-Benzyl-2-hydroxy-4-(5-isobutyryl-1H-imidazol-2-yl)-5-phenyl-pentyl]-carbamic acid tert-butyl ester 
• 150349-13-6 2-<(1R,3S,4S)-4-amino-1-benzyl-3-hydroxy-5-phenylpentyl>-5-(2-methylpropionyl)imidazole 

Relevant articles and documents

Rational design, synthesis, and crystallographic analysis of a hydroxyethylene-based HIV-1 protease inhibitor containing a heterocyclic P1'-P2' amide bond isostere

The rational design and synthesis of a highly potent inhibitor of HIV-1 protease have been accomplished. The inhibitor, SB 206343, is based on a model derived from the structure of the MVT-101/HIV-1 protease complex and contains a 4(5)-acylimidazole ring