1504663-22-2

Basic information

• Product Name: [2-chlorophenyl(dimethylphenylsilyl)methoxy]trimethylsilane
• Synonyms: [2-chlorophenyl(dimethylphenylsilyl)methoxy]trimethylsilane
• CAS NO: 1504663-22-2
• Molecular Weight: 349.02
• Mol File: 1504663-22-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [2-chlorophenyl(dimethylphenylsilyl)methoxy]trimethylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: [2-chlorophenyl(dimethylphenylsilyl)methoxy]trimethylsilane(1504663-22-2)
• EPA Substance Registry System: [2-chlorophenyl(dimethylphenylsilyl)methoxy]trimethylsilane(1504663-22-2)

Safety Data

• Hazardous Substances Data: 1504663-22-2(Hazardous Substances Data)

Upstream product

• 89-98-5 2-chloro-benzaldehyde 
• 768-33-2 phenyldimethylsilyl chloride 
• 1504663-41-5 C₁₅H₁₇ClOSi 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 

Downstream Products

• 156276-21-0 rac-methyl 2-chloromandelate 
• 10421-85-9 2-chloromandelic acid 

Relevant articles and documents

Carboxylation with CO2 via brook rearrangement: Preparation of α-hydroxy acid derivatives

In the presence of CsF, a wide range of α-substituted α-siloxy silanes were carboxylated under a CO2 atmosphere (1 atm) via Brook rearrangement. A variety of α-substituents including aryl, alkenyl, and alkyl groups were tolerated to afford α-hydroxy acids in moderate-to-high yields. One-pot synthesis from aldehydes using PhMe2SiLi and CO 2 was also possible, providing α-hydroxy acids without the isolation of an α-hydroxy silane.