1505-52-8 Usage
Uses
Used in Pharmaceutical Industry:
3-MTAA is used as a precursor for the synthesis of novel bioactive molecules due to its unique molecular structure and potential pharmacological properties. Its ability to serve as a building block for the development of new drugs makes it valuable in the pharmaceutical industry.
Used in Medicinal Chemistry Research:
3-MTAA is used as a subject of research for its anti-inflammatory and analgesic properties, making it a promising candidate for the development of new medications targeting pain and inflammation.
Used in Organic Synthesis:
3-MTAA is utilized as a key intermediate in organic synthesis, where its thianaphthene ring and carboxylic acid group can be further modified to create a variety of chemical compounds with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1505-52-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,0 and 5 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1505-52:
(6*1)+(5*5)+(4*0)+(3*5)+(2*5)+(1*2)=58
58 % 10 = 8
So 1505-52-8 is a valid CAS Registry Number.
InChI:InChI=1/C11H10O2S/c1-7-8-4-2-3-5-9(8)14-10(7)6-11(12)13/h2-5H,6H2,1H3,(H,12,13)/p-1
1505-52-8Relevant academic research and scientific papers
Double-Carboxylation of Two C-H Bonds in 2-Alkylheteroarenes Using LiO- t-Bu/CsF
Shigeno, Masanori,Sasaki, Keita,Nozawa-Kumada, Kanako,Kondo, Yoshinori
supporting information, p. 4515 - 4519 (2019/06/27)
We describe the double-carboxylation of two C-H bonds (i.e., at the benzylic and the β-positions) in 2-alkylheteroarenes using a combination of LiO-t-Bu and CsF. A diverse range of substrates, namely benzothiophene, thiophene, benzofuran, furan, and indole derivatives, are efficiently converted into the doubly carboxylated products. A variety of functionalities (i.e., methyl, methoxy, halogen, cyano, ester, ketone, and amide moieties) are well tolerated.
Nickel-Catalyzed Carboxylation of Benzylic C-N Bonds with CO2
Moragas, Toni,Gaydou, Morgane,Martin, Ruben
supporting information, p. 5053 - 5057 (2016/04/26)
A user-friendly Ni-catalyzed reductive carboxylation of benzylic C-N bonds with CO2 is described. This procedure outperforms state-of-the-art techniques for the carboxylation of benzyl electrophiles by avoiding commonly observed parasitic pathways, such as homodimerization or β-hydride elimination, thus leading to new knowledge in cross-electrophile reactions.
