15057-43-9

Usage

Chemical class

Tetrahydropyridine derivatives

Molar mass

217.27 g/mol

Structural features

a. Benzyl group attached
b. Hydroxy group attached
c. Tetrahydropyridin-3-one ring

Synthetic compound

Yes

Pharmaceutical applications

Potential use in medicinal chemistry

Research and development interest

Therapeutic treatment of various diseases and conditions

Upstream product

• 15057-40-6 ethyl 2-(benzyl(2-oxopropyl)amino)acetate 
• 6436-90-4 ethyl 2-(benzylamino)acetate 

Downstream Products

• 392246-02-5 3-acetoxy-1-benzyl-5-oxo-1,2,5,6-tetrahydropyridine 
• 392246-13-8 (-)-(3S)-3-acetoxy-1-(benzyloxycarbonyl)-5-methyl-1,2,3,6-tetrahydropyridine 
• 392246-00-3 (+/-)-3-acetoxy-1-(benzyloxycarbonyl)-5-methyl-1,2,3,6-tetrahydropyridine 
• 392246-04-7 1-(benzyloxycarbonyl)-5-methyl-3-oxo-1,2,3,6-tetrahydropyridine 
• 392246-15-0 (-)-3S-1-(benzyloxycarbonyl)-3-hydroxy-5-methyl-1,2,3,6-tetrahydropyridine 
• 392246-01-4 (+/-)-1-(benzyloxycarbonyl)-3-hydroxy-5-methyl-1,2,3,6-tetrahydropyridine 
• 392246-03-6 1-benzyl-5-methyl-3-oxo-1,2,3,6-tetrahydropyridine 
• 50866-56-3 1-(benzyl)piperidin-3,5-dione 
• 913831-96-6 cis-1-benzylpiperidine-3,5-diol 

Relevant academic research and scientific papers

Divergent asymmetric synthesis of 3,5-disubstituted piperidines

A divergent synthesis of various 3,5-dioxygenated piperidines with interesting pharmacological properties is described. A mixture of the achiral cis- and racemic trans-3,5-piperidine diol could be efficiently obtained from N-benzylglycinate in five steps

Enantiocontrolled synthesis of 2,3,6-trisubstituted piperidines using (η3-dihydropyridinyl)molybdenum complexes as chiral scaffolds. Total synthesis of (-)-indolizidine 209B

Enantiopure TpMo(CO)2(pyridinyl) complexes were prepared using an efficient and scalable enzymatic kinetic resolution of the precursor to the molybdenum complex. A single TpMo(CO)2(pyridinyl) complex can function as a chiral scaffold