150618-10-3Relevant academic research and scientific papers
Preparation of L-(Phosphonodifluoromethyl) phenylalanine derivatives as non-hydrolyzable mimetics of O-phosphotyrosine
Wrobel, Jay,Dietrich, Arlene
, p. 3543 - 3546 (2007/10/02)
N-t-BOC-L-(Phosphonodifluoromethyl)phenylalanine benzyl ester (1) was prepared in 5 steps from N-t-BOC-L-tyrosine benzyl eser O-triflate (4). Compound 1 was further converted to derivatives 2 and 3 which are potentially suitable for peptide synthesis. Ana
