150618-03-4Relevant articles and documents
Facile syntheses of aryldifluorophosphonate building blocks
Cockerill, G. Stuart,Easterfield, Howard J.,Percy, Jonathan M.
, p. 2601 - 2604 (2007/10/03)
The copper-catalysed zinc phosphonate chemistry described by Yokomatsu and Shibuya can be used directly in the synthesis of phosphotyrosine analogue F2Pmp, and in entering the classical organometallic coupling repertoire via Stille and Suzuki-M
Enantioselective synthesis of N-Boc and N-Fmoc protected diethyl 4-phosphono(difluoromethyl)-L-phenylalanine; agents suitable for the solid-phase synthesis of peptides containing nonhydrolyzable analogues of O-phosphotyrosine
Smyth,Burke Jr.
, p. 551 - 554 (2007/10/02)
Enantioselective convergent syntheses of N-Boc and N-Fmoc protected diethyl 4-phosphono(difluoromethyl)-L-phenylalanine are reported.
Preparation of L-(Phosphonodifluoromethyl) phenylalanine derivatives as non-hydrolyzable mimetics of O-phosphotyrosine
Wrobel, Jay,Dietrich, Arlene
, p. 3543 - 3546 (2007/10/02)
N-t-BOC-L-(Phosphonodifluoromethyl)phenylalanine benzyl ester (1) was prepared in 5 steps from N-t-BOC-L-tyrosine benzyl eser O-triflate (4). Compound 1 was further converted to derivatives 2 and 3 which are potentially suitable for peptide synthesis. Ana