150669-65-1Relevant academic research and scientific papers
Synthesis of hydrophilic Fischer carbene complexes as organometallic marker and PEGylating agent for proteins
Samanta, Debasis,Sawoo, Sudeshna,Patra, Subrata,Ray, Manju,Salmain, Michèle,Sarkar, Amitabha
, p. 5581 - 5590 (2005)
Syntheses of Fischer carbene complexes with various hydrophilic tethers (4, 6a, 6b, 6c, 8a, 8b, 14a, 14b, 15 and 19) are described. The water-soluble carbene complex, 14b, was used to label and pegylate bovine serum albumin (BSA) without affecting its conformation. The red complex, 19, underwent a sharp color change to yellow on reaction with BSA, a feature that is potentially useful for developing assay methods.
MULTIVALENT INHIBITORS OF SERUM AMYLOID P COMPONENT
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Page 61-62, (2008/06/13)
Novel glycerol cyclic pyruvate derivates were prepared and demonstrated to inhibit the binding of an immobilized D-proline derivative to serum amyloid P component (SAP) have been prepared. As such, the compounds of the invention are useful for treating am
