150674-66-1

Basic information

• Product Name: (2S,3R,4R)-4-Acetyl-3-<(methoxycarbonyl)methyl>-2-(methoxymethoxymethyl)-1-(toluene-4-sulfonyl)pyrrolidine
• Synonyms: (2S,3R,4R)-4-Acetyl-3-<(methoxycarbonyl)methyl>-2-(methoxymethoxymethyl)-1-(toluene-4-sulfonyl)pyrrolidine
• CAS NO: 150674-66-1
• Molecular Weight: 413.492
• Mol File: 150674-66-1.mol

Chemical Properties

• CAS DataBase Reference: (2S,3R,4R)-4-Acetyl-3-<(methoxycarbonyl)methyl>-2-(methoxymethoxymethyl)-1-(toluene-4-sulfonyl)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R,4R)-4-Acetyl-3-<(methoxycarbonyl)methyl>-2-(methoxymethoxymethyl)-1-(toluene-4-sulfonyl)pyrrolidine(150674-66-1)
• EPA Substance Registry System: (2S,3R,4R)-4-Acetyl-3-<(methoxycarbonyl)methyl>-2-(methoxymethoxymethyl)-1-(toluene-4-sulfonyl)pyrrolidine(150674-66-1)

Safety Data

• Hazardous Substances Data: 150674-66-1(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 150674-63-8 N-But-2-ynyl-N-((S)-1-methoxymethoxymethyl-allyl)-4-methyl-benzenesulfonamide 
• 150674-62-7 (S)-N-[1-(methoxy)methoxy-3-buten-2-yl]-4-methylbenzenesulfonamide 
• 150674-61-6 ((S)-1-Methoxymethoxymethyl-allyl)-carbamic acid benzyl ester 
• 158839-34-0 (1S,3aS,4S,6aS)-1-(Hydroxymethyl)-4-methyl-2-(toluene-4-sulfonyl)-hexahydrocyclopentapyrrol-5-one 
• 158839-36-2 (3S,3aS)-3-(Hydroxymethyl)-6-methyl-2-(toluene-4-sulfonyl)-2,3,3a,4-tetrahydro-1H-cyclopentapyrrol-5-one 
• 158839-31-7 (3aS,3bS)-6-Methyl-3a,3b,4,7-tetrahydro-3H-2-oxa-7a-azacyclopentapentalene-1,5-dione 
• 158839-32-8 (S)-3-(but-2-ynyl)-4-vinyloxazolidin-2-one 
• 1026379-71-4 (3S,3aS)-3-Hydroxymethyl-6-methyl-2,3,3a,4-tetrahydro-1H-cyclopenta[c]pyrrol-5-one 
• 150674-64-9 (1S,3aS,4S,6aS)-1-(Methoxymethoxymethyl)-4-methyl-2-(toluene-4-sulfonyl)hexahydrocyclopentapyrrol-5-one 
• 150674-65-0 (3S,3aS,6aS)-5-<(Trimethylsilyl)oxy>-3-(methoxymethoxymethyl)-6-methyl-2-(toluene-4-sulfonyl)-1,2,3,3a,4,6a-hexahydrocyclopentapyrrole 
• 150674-67-2 methyl [2S-(2α,3β,4β)]-[2-(methoxymethoxy)methyl-4-(1-methylethenyl)-1-(4-methylphenyl)sulfonyl]-3-pyrrolidineacetate 

Downstream Products

• 487-79-6 (-)-kainic acid 
• 158839-37-3 methyl [2S-(2α,3β,4β)]-[2-(hydroxymethyl)-4-(1-methylethenyl)-1-(4-methylphenyl)sulfonyl]-3-pyrrolidineacetate 
• 301832-55-3 (2S,3S,4S)-3-Carboxymethyl-4-isopropenyl-1-(toluene-4-sulfonyl)-pyrrolidine-2-carboxylic acid 
• 150674-68-3 (2S,3S,4S)-4-Isopropenyl-3-methoxycarbonylmethyl-1-(toluene-4-sulfonyl)-pyrrolidine-2-carboxylic acid 
• 150674-69-4 methyl [2S-(2α,3β,4β)]-[2-(methoxycarbonyl)-4-(1-methylethenyl)-1-(4-methylphenyl)sulfonyl]-3-pyrrolidineacetate 
• 150674-67-2 methyl [2S-(2α,3β,4β)]-[2-(methoxymethoxy)methyl-4-(1-methylethenyl)-1-(4-methylphenyl)sulfonyl]-3-pyrrolidineacetate 

Relevant articles and documents

A Total Synthesis of (-)-α-Kainic Acid Involving a Pauson-Khand Reaction as the Key Step

A synthetic route to (-)-α-kainic acid has been developed based on the Pauson-Khand reaction as a key step for the construction of the bicyclic ring system.In this reaction a built-in oxazolidinone ring serves as a rigid template for good diastereofacial selectivity.

A Total Synthesis of (-)-α-Kainic Acid By the Pauson-Khand Reaction

A total synthetic route to (-)-α-kainic acid has been developed based on the Pauson-Khand reaction as a key reaction for the construction of the bicyclo ring system.