150674-67-2

Upstream product

• 150674-66-1 (2S,3R,4R)-4-Acetyl-3-<(methoxycarbonyl)methyl>-2-(methoxymethoxymethyl)-1-(toluene-4-sulfonyl)pyrrolidine 
• 19493-09-5 Methylenetriphenylphosphorane 
• 188569-97-3 methyl [2S-(2α,3β,4β)]-[2-(methoxymethoxy)methyl-4-(1-methylethenyl)-1-[(4-methylphenyl)sulfonyl]-α-phenylsulfonyl]-3-pyrrolidineacetate 
• 78592-86-6 (E)-3-Methyl-4-(thiophenoxy)-2-buten-1-ol 
• 188569-93-9 [S-(E)]-N-[1-(methoxy)methoxy-3-buten-2-yl]-4-methyl-N-[3-methyl-4-(phenylsulfanyl)-2-butenyl]benzenesulfonamide 
• 188569-96-2 [2S-(2α,3β,4β)]-[2-(methoxymethoxy)methyl-4-(1-methylethenyl)-1-(4-methylphenyl)sulfonyl-3-(phenylsulfonyl)methyl]pyrrolidine 
• 188569-94-0 [2S-(2α,3β,4β)]-[2-(methoxymethoxy)methyl-4-(1-methylethenyl)-1-(4-methylphenyl)sulfonyl-3-(phenylsulfanyl)methyl]pyrrolidine 
• 150674-62-7 (S)-N-[1-(methoxy)methoxy-3-buten-2-yl]-4-methylbenzenesulfonamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 150674-65-0 (3S,3aS,6aS)-5-<(Trimethylsilyl)oxy>-3-(methoxymethoxymethyl)-6-methyl-2-(toluene-4-sulfonyl)-1,2,3,3a,4,6a-hexahydrocyclopentapyrrole 
• 150674-64-9 (1S,3aS,4S,6aS)-1-(Methoxymethoxymethyl)-4-methyl-2-(toluene-4-sulfonyl)hexahydrocyclopentapyrrol-5-one 
• 1026379-71-4 (3S,3aS)-3-Hydroxymethyl-6-methyl-2,3,3a,4-tetrahydro-1H-cyclopenta[c]pyrrol-5-one 
• 158839-32-8 (S)-3-(but-2-ynyl)-4-vinyloxazolidin-2-one 
• 158839-31-7 (3aS,3bS)-6-Methyl-3a,3b,4,7-tetrahydro-3H-2-oxa-7a-azacyclopentapentalene-1,5-dione 

Downstream Products

• 150674-69-4 methyl [2S-(2α,3β,4β)]-[2-(methoxycarbonyl)-4-(1-methylethenyl)-1-(4-methylphenyl)sulfonyl]-3-pyrrolidineacetate 
• 150674-68-3 (2S,3S,4S)-4-Isopropenyl-3-methoxycarbonylmethyl-1-(toluene-4-sulfonyl)-pyrrolidine-2-carboxylic acid 
• 301832-55-3 (2S,3S,4S)-3-Carboxymethyl-4-isopropenyl-1-(toluene-4-sulfonyl)-pyrrolidine-2-carboxylic acid 
• 487-79-6 (-)-kainic acid 
• 150674-66-1 (2S,3R,4R)-4-Acetyl-3-<(methoxycarbonyl)methyl>-2-(methoxymethoxymethyl)-1-(toluene-4-sulfonyl)pyrrolidine 
• 158839-37-3 methyl [2S-(2α,3β,4β)]-[2-(hydroxymethyl)-4-(1-methylethenyl)-1-(4-methylphenyl)sulfonyl]-3-pyrrolidineacetate 

Relevant academic research and scientific papers

An Enantioselective Synthesis of (-)-α-Kainic Acid via Thiyl Radical Addition-Cyclization-Elimination Reaction

An enantioselective synthesis of (-)-α-kainic acid has been achieved via the route involving thiyl radical addition-cyclization-elimination reaction.

Radical cyclization in heterocycle synthesis. Part 10: A concise synthesis of (-)-kainic acid via sulfanyl radical addition-cyclization-elimination reaction

Sulfanyl radical addition-cyclization-elimination of diallylamines in the presence of thiophenol and AIBN gave the 2,3,4-trisubstituted pyrrolidine in high yield. This reaction was extended to a radical cyclization using a catalytic amount of thiophenol. A successful application was demonstrated by the asymmetric synthesis of (-)-kainic acid. (C) 2000 Elsevier Science Ltd.

A Total Synthesis of (-)-α-Kainic Acid Involving a Pauson-Khand Reaction as the Key Step

A synthetic route to (-)-α-kainic acid has been developed based on the Pauson-Khand reaction as a key step for the construction of the bicyclic ring system.In this reaction a built-in oxazolidinone ring serves as a rigid template for good diastereofacial selectivity.

A Total Synthesis of (-)-α-Kainic Acid By the Pauson-Khand Reaction

A total synthetic route to (-)-α-kainic acid has been developed based on the Pauson-Khand reaction as a key reaction for the construction of the bicyclo ring system.